MotifGATA1.H12INVIVO.0.P.B
Gene (human)GATA1
(GeneCards)
Gene synonyms (human)ERYF1, GF1
Gene (mouse)Gata1
Gene synonyms (mouse)Gf-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length18
ConsensusbbbnvvvvnvWGATAASv
GC content51.28%
Information content (bits; total / per base)11.989 / 0.666
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 21 (139) 0.955 0.985 0.908 0.967 0.927 0.961 3.792 4.427 298.796 474.854
Mouse 37 (221) 0.92 0.962 0.849 0.916 0.892 0.937 3.448 3.986 209.26 443.602

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.893 0.849 0.839 0.8 0.763 0.739
best 0.956 0.926 0.935 0.9 0.868 0.838
Methyl HT-SELEX, 1 experiments median 0.956 0.926 0.935 0.9 0.868 0.838
best 0.956 0.926 0.935 0.9 0.868 0.838
Non-Methyl HT-SELEX, 1 experiments median 0.83 0.772 0.743 0.701 0.659 0.64
best 0.83 0.772 0.743 0.701 0.659 0.64

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 3.087 8.873 0.282 0.168
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classOther C4 zinc finger-type factors {2.2} (TFClass)
TF familyC4-GATA-related {2.2.1} (TFClass)
TF subfamilyGATA double {2.2.1.1} (TFClass)
TFClass IDTFClass: 2.2.1.1.1
HGNCHGNC:4170
MGIMGI:95661
EntrezGene (human)GeneID:2623
(SSTAR profile)
EntrezGene (mouse)GeneID:14460
(SSTAR profile)
UniProt ID (human)GATA1_HUMAN
UniProt ID (mouse)GATA1_MOUSE
UniProt AC (human)P15976
(TFClass)
UniProt AC (mouse)P17679
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 21 human, 37 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01135.0231.0224.0410.0
0290.0164.0514.0232.0
03125.0279.0440.0156.0
04169.0282.0313.0236.0
05188.0309.0354.0149.0
06188.0250.0429.0133.0
07182.0263.0418.0137.0
08206.0303.0359.0132.0
09286.0178.0362.0174.0
1095.0506.0320.079.0
11640.057.03.0300.0
120.00.01000.00.0
131000.00.00.00.0
142.02.05.0991.0
15941.07.04.048.0
16849.014.0118.019.0
1799.0175.0685.041.0
18281.0205.0458.056.0
PFM
ACGT
010.1350.2310.2240.41
020.090.1640.5140.232
030.1250.2790.440.156
040.1690.2820.3130.236
050.1880.3090.3540.149
060.1880.250.4290.133
070.1820.2630.4180.137
080.2060.3030.3590.132
090.2860.1780.3620.174
100.0950.5060.320.079
110.640.0570.0030.3
120.00.01.00.0
131.00.00.00.0
140.0020.0020.0050.991
150.9410.0070.0040.048
160.8490.0140.1180.019
170.0990.1750.6850.041
180.2810.2050.4580.056
PWM
ACGT
01-0.61-0.078-0.1090.492
02-1.01-0.4180.717-0.074
03-0.6860.1090.562-0.467
04-0.3880.120.223-0.057
05-0.2830.2110.346-0.513
06-0.2830.00.537-0.625
07-0.3150.050.511-0.596
08-0.1920.1910.36-0.633
090.134-0.3370.368-0.359
10-0.9560.7020.245-1.137
110.936-1.455-3.9750.181
12-4.982-4.9821.381-4.982
131.381-4.982-4.982-4.982
14-4.213-4.213-3.6221.372
151.32-3.362-3.783-1.622
161.218-2.773-0.743-2.497
17-0.916-0.3541.004-1.774
180.116-0.1970.602-1.473
Standard thresholds
P-value Threshold
0.001 4.08866
0.0005 5.23246
0.0001 7.39551