GATA1.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GATA1.H12INVITRO.0.P.B
Gene (human)	GATA1 (GeneCards)
Gene synonyms (human)	ERYF1, GF1
Gene (mouse)	Gata1
Gene synonyms (mouse)	Gf-1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	bbbnnnnnnvAGATAAvv
GC content	43.08%
Information content (bits; total / per base)	12.202 / 0.678
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	21 (139)	0.941	0.98	0.88	0.958	0.927	0.964	3.743	4.388	292.041	446.602
Mouse	37 (221)	0.898	0.96	0.802	0.915	0.88	0.941	3.233	3.894	191.0	405.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.903	0.864	0.848	0.814	0.775	0.751
Overall, 2 experiments	best	0.964	0.937	0.946	0.915	0.876	0.85
Methyl HT-SELEX, 1 experiments	median	0.964	0.937	0.946	0.915	0.876	0.85
Methyl HT-SELEX, 1 experiments	best	0.964	0.937	0.946	0.915	0.876	0.85
Non-Methyl HT-SELEX, 1 experiments	median	0.843	0.792	0.751	0.712	0.675	0.652
Non-Methyl HT-SELEX, 1 experiments	best	0.843	0.792	0.751	0.712	0.675	0.652

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.736	7.087	0.283	0.183

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Other C4 zinc finger-type factors {2.2} (TFClass)
TF family	C4-GATA-related {2.2.1} (TFClass)
TF subfamily	GATA double {2.2.1.1} (TFClass)
TFClass ID	TFClass: 2.2.1.1.1
HGNC	HGNC:4170
MGI	MGI:95661
EntrezGene (human)	GeneID:2623 (SSTAR profile)
EntrezGene (mouse)	GeneID:14460 (SSTAR profile)
UniProt ID (human)	GATA1_HUMAN
UniProt ID (mouse)	GATA1_MOUSE
UniProt AC (human)	P15976 (TFClass)
UniProt AC (mouse)	P17679 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	21 human, 37 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	GATA1.H12INVITRO.0.P.B.pcm
PWM	GATA1.H12INVITRO.0.P.B.pwm
PFM	GATA1.H12INVITRO.0.P.B.pfm
Alignment	GATA1.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	GATA1.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	GATA1.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	GATA1.H12INVITRO.0.P.B_meme_format.meme
Transfac format	GATA1.H12INVITRO.0.P.B_transfac_format.txt
Homer format	GATA1.H12INVITRO.0.P.B_homer_format_0.001.txt GATA1.H12INVITRO.0.P.B_homer_format_0.0005.txt GATA1.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	150.0	184.0	221.0	445.0
02	111.0	130.0	486.0	273.0
03	147.0	223.0	385.0	245.0
04	251.0	184.0	307.0	258.0
05	268.0	203.0	297.0	232.0
06	246.0	184.0	348.0	222.0
07	250.0	198.0	322.0	230.0
08	217.0	236.0	255.0	292.0
09	312.0	161.0	303.0	224.0
10	204.0	404.0	300.0	92.0
11	711.0	17.0	5.0	267.0
12	0.0	0.0	1000.0	0.0
13	1000.0	0.0	0.0	0.0
14	0.0	0.0	1.0	999.0
15	964.0	2.0	1.0	33.0
16	962.0	3.0	16.0	19.0
17	139.0	139.0	694.0	28.0
18	394.0	188.0	358.0	60.0

PFM

	A	C	G	T
01	0.15	0.184	0.221	0.445
02	0.111	0.13	0.486	0.273
03	0.147	0.223	0.385	0.245
04	0.251	0.184	0.307	0.258
05	0.268	0.203	0.297	0.232
06	0.246	0.184	0.348	0.222
07	0.25	0.198	0.322	0.23
08	0.217	0.236	0.255	0.292
09	0.312	0.161	0.303	0.224
10	0.204	0.404	0.3	0.092
11	0.711	0.017	0.005	0.267
12	0.0	0.0	1.0	0.0
13	1.0	0.0	0.0	0.0
14	0.0	0.0	0.001	0.999
15	0.964	0.002	0.001	0.033
16	0.962	0.003	0.016	0.019
17	0.139	0.139	0.694	0.028
18	0.394	0.188	0.358	0.06

PWM

	A	C	G	T
01	-0.506	-0.304	-0.122	0.574
02	-0.803	-0.648	0.661	0.087
03	-0.526	-0.113	0.429	-0.02
04	0.004	-0.304	0.204	0.031
05	0.069	-0.207	0.171	-0.074
06	-0.016	-0.304	0.329	-0.118
07	0.0	-0.231	0.252	-0.083
08	-0.141	-0.057	0.02	0.154
09	0.22	-0.436	0.191	-0.109
10	-0.202	0.477	0.181	-0.988
11	1.041	-2.598	-3.622	0.065
12	-4.982	-4.982	1.381	-4.982
13	1.381	-4.982	-4.982	-4.982
14	-4.982	-4.982	-4.525	1.38
15	1.345	-4.213	-4.525	-1.981
16	1.342	-3.975	-2.653	-2.497
17	-0.582	-0.582	1.017	-2.136
18	0.452	-0.283	0.357	-1.406

Standard thresholds

P-value	Threshold
0.001	3.67581
0.0005	4.96176
0.0001	7.55436