MotifGABPA.H12CORE.0.PSM.A
Gene (human)GABPA
(GeneCards)
Gene synonyms (human)E4TF1A
Gene (mouse)Gabpa
Gene synonyms (mouse)E4tf1a
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length12
ConsensusnRCCGGAAGYdn
GC content55.45%
Information content (bits; total / per base)14.285 / 1.19
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9955

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 36 (228) 0.966 0.981 0.928 0.968 0.945 0.969 4.124 4.662 331.171 437.328
Mouse 5 (33) 0.971 0.985 0.935 0.958 0.959 0.971 4.379 4.792 260.377 405.301

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.999 0.998 0.999 0.998 0.997 0.995
best 0.999 0.999 0.999 0.998 0.998 0.997
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.999 0.998 0.998 0.997
best 0.999 0.999 0.999 0.998 0.998 0.997
Non-Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.998 0.997 0.995 0.993
best 0.999 0.998 0.998 0.997 0.995 0.993

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 6.182 11.081 0.254 0.197
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyETS-like {3.5.2.1} (TFClass)
TFClass IDTFClass: 3.5.2.1.5
HGNCHGNC:4071
MGIMGI:95610
EntrezGene (human)GeneID:2551
(SSTAR profile)
EntrezGene (mouse)GeneID:14390
(SSTAR profile)
UniProt ID (human)GABPA_HUMAN
UniProt ID (mouse)GABPA_MOUSE
UniProt AC (human)Q06546
(TFClass)
UniProt AC (mouse)Q00422
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 36 human, 5 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013552.02049.02305.02049.0
027540.5193.51273.5947.5
03273.09033.0622.027.0
04878.09069.03.05.0
050.01.09954.00.0
060.00.09955.00.0
079955.00.00.00.0
089721.00.00.0234.0
091185.089.08680.01.0
10171.01681.0580.07523.0
113285.01277.03774.01619.0
122788.02621.03077.01469.0
PFM
ACGT
010.3570.2060.2320.206
020.7570.0190.1280.095
030.0270.9070.0620.003
040.0880.9110.00.001
050.00.01.00.0
060.00.01.00.0
071.00.00.00.0
080.9760.00.00.024
090.1190.0090.8720.0
100.0170.1690.0580.756
110.330.1280.3790.163
120.280.2630.3090.148
PWM
ACGT
010.355-0.194-0.077-0.194
021.108-2.543-0.669-0.964
03-2.2031.288-1.384-4.443
04-1.041.292-6.152-5.832
05-6.987-6.6261.386-6.987
06-6.987-6.9871.386-6.987
071.386-6.987-6.987-6.987
081.362-6.987-6.987-2.355
09-0.741-3.3061.249-6.626
10-2.665-0.392-1.4531.106
110.277-0.6660.416-0.429
120.1130.0520.212-0.527
Standard thresholds
P-value Threshold
0.001 1.66983
0.0005 3.463435
0.0001 6.75784