FOXP3.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXP3.H12INVIVO.0.P.B
Gene (human)	FOXP3 (GeneCards)
Gene synonyms (human)	IPEX
Gene (mouse)	Foxp3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	bbbTGTTTdY
GC content	36.32%
Information content (bits; total / per base)	8.789 / 0.879
Data sources	ChIP-Seq
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	4 (24)	0.61	0.737	0.419	0.585	0.693	0.791	1.894	2.566	4.64	75.143

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXP {3.3.1.16} (TFClass)
TFClass ID	TFClass: 3.3.1.16.3
HGNC	HGNC:6106
MGI	MGI:1891436
EntrezGene (human)	GeneID:50943 (SSTAR profile)
EntrezGene (mouse)	GeneID:20371 (SSTAR profile)
UniProt ID (human)	FOXP3_HUMAN
UniProt ID (mouse)	FOXP3_MOUSE
UniProt AC (human)	Q9BZS1 (TFClass)
UniProt AC (mouse)	Q99JB6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	FOXP3.H12INVIVO.0.P.B.pcm
PWM	FOXP3.H12INVIVO.0.P.B.pwm
PFM	FOXP3.H12INVIVO.0.P.B.pfm
Alignment	FOXP3.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	FOXP3.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	FOXP3.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	FOXP3.H12INVIVO.0.P.B_meme_format.meme
Transfac format	FOXP3.H12INVIVO.0.P.B_transfac_format.txt
Homer format	FOXP3.H12INVIVO.0.P.B_homer_format_0.001.txt FOXP3.H12INVIVO.0.P.B_homer_format_0.0005.txt FOXP3.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	110.0	190.0	273.0	424.0
02	50.0	296.0	223.0	428.0
03	49.0	319.0	123.0	506.0
04	5.0	10.0	22.0	960.0
05	37.0	48.0	888.0	24.0
06	9.0	33.0	19.0	936.0
07	8.0	13.0	86.0	890.0
08	19.0	11.0	118.0	849.0
09	352.0	124.0	248.0	273.0
10	14.0	497.0	80.0	406.0

PFM

	A	C	G	T
01	0.11	0.191	0.274	0.425
02	0.05	0.297	0.224	0.429
03	0.049	0.32	0.123	0.508
04	0.005	0.01	0.022	0.963
05	0.037	0.048	0.891	0.024
06	0.009	0.033	0.019	0.939
07	0.008	0.013	0.086	0.893
08	0.019	0.011	0.118	0.852
09	0.353	0.124	0.249	0.274
10	0.014	0.498	0.08	0.407

PWM

	A	C	G	T
01	-0.809	-0.269	0.09	0.528
02	-1.579	0.171	-0.11	0.538
03	-1.599	0.245	-0.699	0.705
04	-3.619	-3.064	-2.359	1.343
05	-1.869	-1.619	1.266	-2.278
06	-3.153	-1.978	-2.494	1.318
07	-3.251	-2.836	-1.051	1.268
08	-2.494	-2.982	-0.74	1.221
09	0.343	-0.691	-0.005	0.09
10	-2.77	0.687	-1.122	0.485

Standard thresholds

P-value	Threshold
0.001	4.929815
0.0005	5.74237
0.0001	7.46888