| Motif | FOXP1.H12RSNP.0.PS.A |
| Gene (human) | FOXP1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Foxp1 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | FOXP1.H12RSNP.0.PS.A |
| Gene (human) | FOXP1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Foxp1 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 8 |
| Consensus | TGTTTMCW |
| GC content | 30.72% |
| Information content (bits; total / per base) | 10.654 / 1.332 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 1001 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 11 (71) | 0.658 | 0.87 | 0.544 | 0.769 | 0.693 | 0.892 | 1.953 | 3.04 | 34.481 | 167.31 |
| Mouse | 4 (22) | 0.607 | 0.745 | 0.505 | 0.633 | 0.648 | 0.75 | 1.765 | 2.289 | 12.595 | 164.469 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 1 experiments | median | 0.842 | 0.793 | 0.75 | 0.713 | 0.651 | 0.642 |
| best | 0.842 | 0.793 | 0.75 | 0.713 | 0.651 | 0.642 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 3.258 | 1.947 | 0.126 | 0.141 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | FOX {3.3.1} (TFClass) |
| TF subfamily | FOXP {3.3.1.16} (TFClass) |
| TFClass ID | TFClass: 3.3.1.16.1 |
| HGNC | HGNC:3823 |
| MGI | MGI:1914004 |
| EntrezGene (human) | GeneID:27086 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:108655 (SSTAR profile) |
| UniProt ID (human) | FOXP1_HUMAN |
| UniProt ID (mouse) | FOXP1_MOUSE |
| UniProt AC (human) | Q9H334 (TFClass) |
| UniProt AC (mouse) | P58462 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 11 human, 4 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 0 |
| PCM | FOXP1.H12RSNP.0.PS.A.pcm |
| PWM | FOXP1.H12RSNP.0.PS.A.pwm |
| PFM | FOXP1.H12RSNP.0.PS.A.pfm |
| Alignment | FOXP1.H12RSNP.0.PS.A.words.tsv |
| Threshold to P-value map | FOXP1.H12RSNP.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | FOXP1.H12RSNP.0.PS.A_jaspar_format.txt |
| MEME format | FOXP1.H12RSNP.0.PS.A_meme_format.meme |
| Transfac format | FOXP1.H12RSNP.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 15.0 | 21.0 | 3.0 | 962.0 |
| 02 | 58.0 | 1.0 | 940.0 | 2.0 |
| 03 | 169.0 | 9.0 | 3.0 | 820.0 |
| 04 | 6.0 | 12.0 | 19.0 | 964.0 |
| 05 | 1.0 | 9.0 | 32.0 | 959.0 |
| 06 | 654.0 | 266.0 | 68.0 | 13.0 |
| 07 | 8.0 | 890.0 | 8.0 | 95.0 |
| 08 | 499.0 | 165.0 | 14.0 | 323.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.015 | 0.021 | 0.003 | 0.961 |
| 02 | 0.058 | 0.001 | 0.939 | 0.002 |
| 03 | 0.169 | 0.009 | 0.003 | 0.819 |
| 04 | 0.006 | 0.012 | 0.019 | 0.963 |
| 05 | 0.001 | 0.009 | 0.032 | 0.958 |
| 06 | 0.653 | 0.266 | 0.068 | 0.013 |
| 07 | 0.008 | 0.889 | 0.008 | 0.095 |
| 08 | 0.499 | 0.165 | 0.014 | 0.323 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -2.712 | -2.406 | -3.976 | 1.341 |
| 02 | -1.44 | -4.526 | 1.318 | -4.214 |
| 03 | -0.389 | -3.157 | -3.976 | 1.182 |
| 04 | -3.485 | -2.91 | -2.498 | 1.344 |
| 05 | -4.526 | -3.157 | -2.011 | 1.338 |
| 06 | 0.956 | 0.061 | -1.285 | -2.84 |
| 07 | -3.254 | 1.264 | -3.254 | -0.957 |
| 08 | 0.687 | -0.413 | -2.774 | 0.254 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.50764 |
| 0.0005 | 5.37236 |
| 0.0001 | 7.452905 |