FOXP1.H12INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXP1.H12INVITRO.0.PS.A
Gene (human)	FOXP1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Foxp1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	ndTGTTKdYbdYn
GC content	37.7%
Information content (bits; total / per base)	10.151 / 0.781
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9260

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	11 (71)	0.615	0.864	0.442	0.792	0.657	0.884	1.711	3.2	26.921	219.284
Mouse	4 (22)	0.601	0.759	0.476	0.609	0.657	0.771	1.834	2.264	13.403	166.081

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.923	0.887	0.839	0.805	0.71	0.707
Non-Methyl HT-SELEX, 1 experiments	best	0.923	0.887	0.839	0.805	0.71	0.707

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.573	1.398	0.051	0.103

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXP {3.3.1.16} (TFClass)
TFClass ID	TFClass: 3.3.1.16.1
HGNC	HGNC:3823
MGI	MGI:1914004
EntrezGene (human)	GeneID:27086 (SSTAR profile)
EntrezGene (mouse)	GeneID:108655 (SSTAR profile)
UniProt ID (human)	FOXP1_HUMAN
UniProt ID (mouse)	FOXP1_MOUSE
UniProt AC (human)	Q9H334 (TFClass)
UniProt AC (mouse)	P58462 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	11 human, 4 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	FOXP1.H12INVITRO.0.PS.A.pcm
PWM	FOXP1.H12INVITRO.0.PS.A.pwm
PFM	FOXP1.H12INVITRO.0.PS.A.pfm
Alignment	FOXP1.H12INVITRO.0.PS.A.words.tsv
Threshold to P-value map	FOXP1.H12INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	FOXP1.H12INVITRO.0.PS.A_jaspar_format.txt
MEME format	FOXP1.H12INVITRO.0.PS.A_meme_format.meme
Transfac format	FOXP1.H12INVITRO.0.PS.A_transfac_format.txt
Homer format	FOXP1.H12INVITRO.0.PS.A_homer_format_0.001.txt FOXP1.H12INVITRO.0.PS.A_homer_format_0.0005.txt FOXP1.H12INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1864.5	2206.5	3082.5	2106.5
02	1479.0	1267.0	1586.0	4928.0
03	31.0	214.0	41.0	8974.0
04	483.0	68.0	8709.0	0.0
05	0.0	98.0	2.0	9160.0
06	0.0	18.0	3.0	9239.0
07	103.0	56.0	4046.0	5055.0
08	4406.0	375.0	1319.0	3160.0
09	59.0	4156.0	1510.0	3535.0
10	775.0	3083.0	2390.0	3012.0
11	3545.0	836.0	3071.0	1808.0
12	1070.75	1317.75	917.75	5953.75
13	1737.0	2406.0	2610.0	2507.0

PFM

	A	C	G	T
01	0.201	0.238	0.333	0.227
02	0.16	0.137	0.171	0.532
03	0.003	0.023	0.004	0.969
04	0.052	0.007	0.94	0.0
05	0.0	0.011	0.0	0.989
06	0.0	0.002	0.0	0.998
07	0.011	0.006	0.437	0.546
08	0.476	0.04	0.142	0.341
09	0.006	0.449	0.163	0.382
10	0.084	0.333	0.258	0.325
11	0.383	0.09	0.332	0.195
12	0.116	0.142	0.099	0.643
13	0.188	0.26	0.282	0.271

PWM

	A	C	G	T
01	-0.216	-0.048	0.286	-0.094
02	-0.447	-0.602	-0.378	0.755
03	-4.243	-2.372	-3.98	1.354
04	-1.563	-3.496	1.324	-6.923
05	-6.923	-3.14	-6.293	1.375
06	-6.923	-4.738	-6.084	1.383
07	-3.091	-3.683	0.558	0.78
08	0.643	-1.815	-0.562	0.311
09	-3.633	0.585	-0.427	0.423
10	-1.092	0.286	0.032	0.263
11	0.426	-1.017	0.282	-0.247
12	-0.77	-0.563	-0.924	0.944
13	-0.287	0.039	0.12	0.08

Standard thresholds

P-value	Threshold
0.001	4.81806
0.0005	5.89521
0.0001	7.602975