FOXP1.H12CORE.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXP1.H12CORE.0.PS.A
Gene (human)	FOXP1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Foxp1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	9
Consensus	nTGTTTACh
GC content	32.56%
Information content (bits; total / per base)	11.447 / 1.272
Data sources	ChIP-Seq + HT-SELEX
Aligned words	447

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	11 (71)	0.683	0.903	0.592	0.828	0.712	0.92	2.172	3.409	48.538	212.699
Mouse	4 (22)	0.637	0.799	0.536	0.695	0.673	0.802	2.043	2.713	22.959	195.796

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.883	0.835	0.794	0.755	0.683	0.674
Non-Methyl HT-SELEX, 1 experiments	best	0.883	0.835	0.794	0.755	0.683	0.674

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.984	1.682	0.11	0.15

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXP {3.3.1.16} (TFClass)
TFClass ID	TFClass: 3.3.1.16.1
HGNC	HGNC:3823
MGI	MGI:1914004
EntrezGene (human)	GeneID:27086 (SSTAR profile)
EntrezGene (mouse)	GeneID:108655 (SSTAR profile)
UniProt ID (human)	FOXP1_HUMAN
UniProt ID (mouse)	FOXP1_MOUSE
UniProt AC (human)	Q9H334 (TFClass)
UniProt AC (mouse)	P58462 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	11 human, 4 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	FOXP1.H12CORE.0.PS.A.pcm
PWM	FOXP1.H12CORE.0.PS.A.pwm
PFM	FOXP1.H12CORE.0.PS.A.pfm
Alignment	FOXP1.H12CORE.0.PS.A.words.tsv
Threshold to P-value map	FOXP1.H12CORE.0.PS.A.thr
Motif in other formats
JASPAR format	FOXP1.H12CORE.0.PS.A_jaspar_format.txt
MEME format	FOXP1.H12CORE.0.PS.A_meme_format.meme
Transfac format	FOXP1.H12CORE.0.PS.A_transfac_format.txt
Homer format	FOXP1.H12CORE.0.PS.A_homer_format_0.001.txt FOXP1.H12CORE.0.PS.A_homer_format_0.0005.txt FOXP1.H12CORE.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	59.0	128.0	145.0	115.0
02	3.0	1.0	7.0	436.0
03	15.0	1.0	430.0	1.0
04	5.0	1.0	0.0	441.0
05	1.0	1.0	21.0	424.0
06	0.0	1.0	64.0	382.0
07	395.0	17.0	25.0	10.0
08	4.0	358.0	2.0	83.0
09	134.0	100.0	8.0	205.0

PFM

	A	C	G	T
01	0.132	0.286	0.324	0.257
02	0.007	0.002	0.016	0.975
03	0.034	0.002	0.962	0.002
04	0.011	0.002	0.0	0.987
05	0.002	0.002	0.047	0.949
06	0.0	0.002	0.143	0.855
07	0.884	0.038	0.056	0.022
08	0.009	0.801	0.004	0.186
09	0.3	0.224	0.018	0.459

PWM

	A	C	G	T
01	-0.627	0.134	0.257	0.028
02	-3.22	-3.803	-2.587	1.351
03	-1.925	-3.803	1.338	-3.803
04	-2.854	-3.803	-4.307	1.363
05	-3.803	-3.803	-1.615	1.324
06	-4.307	-3.803	-0.547	1.22
07	1.253	-1.811	-1.452	-2.285
08	-3.02	1.155	-3.47	-0.293
09	0.179	-0.11	-2.476	0.601

Standard thresholds

P-value	Threshold
0.001	4.347515
0.0005	5.25085
0.0001	7.463125