FOXO6.H12INVITRO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXO6.H12INVITRO.0.S.B
Gene (human)	FOXO6 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Foxo6
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	nbdTGTTTAYdn
GC content	35.42%
Information content (bits; total / per base)	11.854 / 0.988
Data sources	HT-SELEX
Aligned words	9701

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.955	0.937	0.844	0.831	0.695	0.712
Non-Methyl HT-SELEX, 2 experiments	best	0.969	0.958	0.866	0.855	0.707	0.728

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.597	0.278	0.476	0.359

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXO {3.3.1.15} (TFClass)
TFClass ID	TFClass: 3.3.1.15.5
HGNC	HGNC:24814
MGI	MGI:2676586
EntrezGene (human)
EntrezGene (mouse)	GeneID:329934 (SSTAR profile)
UniProt ID (human)	FOXO6_HUMAN
UniProt ID (mouse)	FOXO6_MOUSE
UniProt AC (human)	A8MYZ6 (TFClass)
UniProt AC (mouse)	Q70KY4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	FOXO6.H12INVITRO.0.S.B.pcm
PWM	FOXO6.H12INVITRO.0.S.B.pwm
PFM	FOXO6.H12INVITRO.0.S.B.pfm
Alignment	FOXO6.H12INVITRO.0.S.B.words.tsv
Threshold to P-value map	FOXO6.H12INVITRO.0.S.B.thr
Motif in other formats
JASPAR format	FOXO6.H12INVITRO.0.S.B_jaspar_format.txt
MEME format	FOXO6.H12INVITRO.0.S.B_meme_format.meme
Transfac format	FOXO6.H12INVITRO.0.S.B_transfac_format.txt
Homer format	FOXO6.H12INVITRO.0.S.B_homer_format_0.001.txt FOXO6.H12INVITRO.0.S.B_homer_format_0.0005.txt FOXO6.H12INVITRO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2740.0	2108.0	1834.0	3019.0
02	1300.5	4002.5	2881.5	1516.5
03	3046.0	758.0	1430.0	4467.0
04	60.0	144.0	47.0	9450.0
05	138.0	66.0	9494.0	3.0
06	6.0	30.0	1.0	9664.0
07	0.0	3.0	6.0	9692.0
08	6.0	77.0	1427.0	8191.0
09	8604.0	179.0	112.0	806.0
10	74.0	7195.0	287.0	2145.0
11	2336.25	1644.25	3850.25	1870.25
12	2306.25	2054.25	1602.25	3738.25

PFM

	A	C	G	T
01	0.282	0.217	0.189	0.311
02	0.134	0.413	0.297	0.156
03	0.314	0.078	0.147	0.46
04	0.006	0.015	0.005	0.974
05	0.014	0.007	0.979	0.0
06	0.001	0.003	0.0	0.996
07	0.0	0.0	0.001	0.999
08	0.001	0.008	0.147	0.844
09	0.887	0.018	0.012	0.083
10	0.008	0.742	0.03	0.221
11	0.241	0.169	0.397	0.193
12	0.238	0.212	0.165	0.385

PWM

	A	C	G	T
01	0.122	-0.14	-0.279	0.219
02	-0.622	0.501	0.172	-0.469
03	0.228	-1.161	-0.528	0.61
04	-3.663	-2.809	-3.897	1.359
05	-2.851	-3.571	1.364	-6.128
06	-5.679	-4.32	-6.602	1.382
07	-6.964	-6.128	-5.679	1.385
08	-5.679	-3.421	-0.53	1.216
09	1.266	-2.595	-3.056	-1.1
10	-3.46	1.087	-2.127	-0.123
11	-0.037	-0.388	0.462	-0.26
12	-0.05	-0.166	-0.414	0.432

Standard thresholds

P-value	Threshold
0.001	3.82423
0.0005	4.997015
0.0001	7.58413