MotifFOXO4.H12INVIVO.0.SM.D
Gene (human)FOXO4
(GeneCards)
Gene synonyms (human)AFX, AFX1, MLLT7
Gene (mouse)Foxo4
Gene synonyms (mouse)Afx, Afx1, Fkhr3, Mllt7
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length11
ConsensusndTGTTTWbdn
GC content35.45%
Information content (bits; total / per base)9.765 / 0.888
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8408

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.771 0.731 0.699 0.67 0.634 0.624
best 0.866 0.807 0.808 0.753 0.737 0.691
Methyl HT-SELEX, 1 experiments median 0.849 0.781 0.802 0.74 0.737 0.691
best 0.849 0.781 0.802 0.74 0.737 0.691
Non-Methyl HT-SELEX, 3 experiments median 0.692 0.68 0.596 0.599 0.551 0.559
best 0.866 0.807 0.808 0.753 0.717 0.688
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXO {3.3.1.15} (TFClass)
TFClass IDTFClass: 3.3.1.15.3
HGNCHGNC:7139
MGIMGI:1891915
EntrezGene (human)GeneID:4303
(SSTAR profile)
EntrezGene (mouse)GeneID:54601
(SSTAR profile)
UniProt ID (human)FOXO4_HUMAN
UniProt ID (mouse)FOXO4_MOUSE
UniProt AC (human)P98177
(TFClass)
UniProt AC (mouse)Q9WVH3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011768.02061.02586.01993.0
021468.0998.01488.04454.0
0394.0176.099.08039.0
04418.01.07989.00.0
050.00.00.08408.0
061.00.0134.08273.0
0718.0146.02124.06120.0
085674.0422.0643.01669.0
09273.04045.01215.02875.0
101773.01342.03314.01979.0
111759.251535.252467.252646.25
PFM
ACGT
010.210.2450.3080.237
020.1750.1190.1770.53
030.0110.0210.0120.956
040.050.00.950.0
050.00.00.01.0
060.00.00.0160.984
070.0020.0170.2530.728
080.6750.050.0760.199
090.0320.4810.1450.342
100.2110.160.3940.235
110.2090.1830.2930.315
PWM
ACGT
01-0.173-0.020.207-0.053
02-0.359-0.744-0.3450.75
03-3.085-2.468-3.0341.341
04-1.611-6.471.334-6.837
05-6.837-6.837-6.8371.385
06-6.47-6.837-2.7371.369
07-4.643-2.6530.011.068
080.992-1.601-1.182-0.23
09-2.0340.654-0.5470.313
10-0.17-0.4480.455-0.06
11-0.178-0.3140.160.23
Standard thresholds
P-value Threshold
0.001 4.96218
0.0005 5.965925
0.0001 7.548625