| Motif | FOXO4.H12INVIVO.0.SM.D |
| Gene (human) | FOXO4 (GeneCards) |
| Gene synonyms (human) | AFX, AFX1, MLLT7 |
| Gene (mouse) | Foxo4 |
| Gene synonyms (mouse) | Afx, Afx1, Fkhr3, Mllt7 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | FOXO4.H12INVIVO.0.SM.D |
| Gene (human) | FOXO4 (GeneCards) |
| Gene synonyms (human) | AFX, AFX1, MLLT7 |
| Gene (mouse) | Foxo4 |
| Gene synonyms (mouse) | Afx, Afx1, Fkhr3, Mllt7 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 11 |
| Consensus | ndTGTTTWbdn |
| GC content | 35.45% |
| Information content (bits; total / per base) | 9.765 / 0.888 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 8408 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.771 | 0.731 | 0.699 | 0.67 | 0.634 | 0.624 |
| best | 0.866 | 0.807 | 0.808 | 0.753 | 0.737 | 0.691 | |
| Methyl HT-SELEX, 1 experiments | median | 0.849 | 0.781 | 0.802 | 0.74 | 0.737 | 0.691 |
| best | 0.849 | 0.781 | 0.802 | 0.74 | 0.737 | 0.691 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.692 | 0.68 | 0.596 | 0.599 | 0.551 | 0.559 |
| best | 0.866 | 0.807 | 0.808 | 0.753 | 0.717 | 0.688 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | FOX {3.3.1} (TFClass) |
| TF subfamily | FOXO {3.3.1.15} (TFClass) |
| TFClass ID | TFClass: 3.3.1.15.3 |
| HGNC | HGNC:7139 |
| MGI | MGI:1891915 |
| EntrezGene (human) | GeneID:4303 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:54601 (SSTAR profile) |
| UniProt ID (human) | FOXO4_HUMAN |
| UniProt ID (mouse) | FOXO4_MOUSE |
| UniProt AC (human) | P98177 (TFClass) |
| UniProt AC (mouse) | Q9WVH3 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | FOXO4.H12INVIVO.0.SM.D.pcm |
| PWM | FOXO4.H12INVIVO.0.SM.D.pwm |
| PFM | FOXO4.H12INVIVO.0.SM.D.pfm |
| Alignment | FOXO4.H12INVIVO.0.SM.D.words.tsv |
| Threshold to P-value map | FOXO4.H12INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | FOXO4.H12INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | FOXO4.H12INVIVO.0.SM.D_meme_format.meme |
| Transfac format | FOXO4.H12INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1768.0 | 2061.0 | 2586.0 | 1993.0 |
| 02 | 1468.0 | 998.0 | 1488.0 | 4454.0 |
| 03 | 94.0 | 176.0 | 99.0 | 8039.0 |
| 04 | 418.0 | 1.0 | 7989.0 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 8408.0 |
| 06 | 1.0 | 0.0 | 134.0 | 8273.0 |
| 07 | 18.0 | 146.0 | 2124.0 | 6120.0 |
| 08 | 5674.0 | 422.0 | 643.0 | 1669.0 |
| 09 | 273.0 | 4045.0 | 1215.0 | 2875.0 |
| 10 | 1773.0 | 1342.0 | 3314.0 | 1979.0 |
| 11 | 1759.25 | 1535.25 | 2467.25 | 2646.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.21 | 0.245 | 0.308 | 0.237 |
| 02 | 0.175 | 0.119 | 0.177 | 0.53 |
| 03 | 0.011 | 0.021 | 0.012 | 0.956 |
| 04 | 0.05 | 0.0 | 0.95 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 0.0 | 0.0 | 0.016 | 0.984 |
| 07 | 0.002 | 0.017 | 0.253 | 0.728 |
| 08 | 0.675 | 0.05 | 0.076 | 0.199 |
| 09 | 0.032 | 0.481 | 0.145 | 0.342 |
| 10 | 0.211 | 0.16 | 0.394 | 0.235 |
| 11 | 0.209 | 0.183 | 0.293 | 0.315 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.173 | -0.02 | 0.207 | -0.053 |
| 02 | -0.359 | -0.744 | -0.345 | 0.75 |
| 03 | -3.085 | -2.468 | -3.034 | 1.341 |
| 04 | -1.611 | -6.47 | 1.334 | -6.837 |
| 05 | -6.837 | -6.837 | -6.837 | 1.385 |
| 06 | -6.47 | -6.837 | -2.737 | 1.369 |
| 07 | -4.643 | -2.653 | 0.01 | 1.068 |
| 08 | 0.992 | -1.601 | -1.182 | -0.23 |
| 09 | -2.034 | 0.654 | -0.547 | 0.313 |
| 10 | -0.17 | -0.448 | 0.455 | -0.06 |
| 11 | -0.178 | -0.314 | 0.16 | 0.23 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.96218 |
| 0.0005 | 5.965925 |
| 0.0001 | 7.548625 |