MotifFOXO3.H12CORE.0.PS.A
Gene (human)FOXO3
(GeneCards)
Gene synonyms (human)FKHRL1, FOXO3A
Gene (mouse)Foxo3
Gene synonyms (mouse)Fkhr2, Foxo3a
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length9
ConsensusbbTGTTTWC
GC content36.97%
Information content (bits; total / per base)11.178 / 1.242
Data sourcesChIP-Seq + HT-SELEX
Aligned words995

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.867 0.877 0.789 0.809 0.888 0.902 3.453 3.585 255.071 276.237

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.72 0.688 0.627 0.615 0.568 0.571
best 0.727 0.696 0.631 0.619 0.57 0.574
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXO {3.3.1.15} (TFClass)
TFClass IDTFClass: 3.3.1.15.2
HGNCHGNC:3821
MGIMGI:1890081
EntrezGene (human)GeneID:2309
(SSTAR profile)
EntrezGene (mouse)GeneID:56484
(SSTAR profile)
UniProt ID (human)FOXO3_HUMAN
UniProt ID (mouse)FOXO3_MOUSE
UniProt AC (human)O43524
(TFClass)
UniProt AC (mouse)Q9WVH4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
0193.0408.0286.0208.0
0256.0383.0152.0404.0
037.00.03.0985.0
0429.00.0963.03.0
050.06.05.0984.0
060.02.015.0978.0
072.03.0142.0848.0
08719.099.040.0137.0
093.0787.017.0188.0
PFM
ACGT
010.0930.410.2870.209
020.0560.3850.1530.406
030.0070.00.0030.99
040.0290.00.9680.003
050.00.0060.0050.989
060.00.0020.0150.983
070.0020.0030.1430.852
080.7230.0990.040.138
090.0030.7910.0170.189
PWM
ACGT
01-0.9720.4920.139-0.178
02-1.4680.429-0.4880.482
03-3.357-4.978-3.971.371
04-2.098-4.9781.348-3.97
05-4.978-3.479-3.6171.37
06-4.978-4.208-2.7061.364
07-4.208-3.97-0.5551.222
081.057-0.911-1.792-0.591
09-3.971.147-2.593-0.278
Standard thresholds
P-value Threshold
0.001 4.26151
0.0005 5.45083
0.0001 7.69086