| Motif | FOXO1.H12INVIVO.0.PS.A |
| Gene (human) | FOXO1 (GeneCards) |
| Gene synonyms (human) | FKHR, FOXO1A |
| Gene (mouse) | Foxo1 |
| Gene synonyms (mouse) | Fkhr, Foxo1a |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | FOXO1.H12INVIVO.0.PS.A |
| Gene (human) | FOXO1 (GeneCards) |
| Gene synonyms (human) | FKHR, FOXO1A |
| Gene (mouse) | Foxo1 |
| Gene synonyms (mouse) | Fkhr, Foxo1a |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 9 |
| Consensus | bbTGTTKWC |
| GC content | 42.68% |
| Information content (bits; total / per base) | 9.905 / 1.101 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 1002 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 3 (20) | 0.835 | 0.861 | 0.718 | 0.762 | 0.836 | 0.859 | 2.65 | 2.794 | 86.966 | 149.155 |
| Mouse | 12 (78) | 0.729 | 0.903 | 0.665 | 0.854 | 0.736 | 0.901 | 2.369 | 3.439 | 72.569 | 424.77 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.666 | 0.634 | 0.6 | 0.584 | 0.558 | 0.554 |
| best | 0.696 | 0.663 | 0.615 | 0.601 | 0.565 | 0.564 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.624 | 0.24 | 0.544 | 0.343 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | FOX {3.3.1} (TFClass) |
| TF subfamily | FOXO {3.3.1.15} (TFClass) |
| TFClass ID | TFClass: 3.3.1.15.1 |
| HGNC | HGNC:3819 |
| MGI | MGI:1890077 |
| EntrezGene (human) | GeneID:2308 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:56458 (SSTAR profile) |
| UniProt ID (human) | FOXO1_HUMAN |
| UniProt ID (mouse) | FOXO1_MOUSE |
| UniProt AC (human) | Q12778 (TFClass) |
| UniProt AC (mouse) | Q9R1E0 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 12 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | FOXO1.H12INVIVO.0.PS.A.pcm |
| PWM | FOXO1.H12INVIVO.0.PS.A.pwm |
| PFM | FOXO1.H12INVIVO.0.PS.A.pfm |
| Alignment | FOXO1.H12INVIVO.0.PS.A.words.tsv |
| Threshold to P-value map | FOXO1.H12INVIVO.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | FOXO1.H12INVIVO.0.PS.A_jaspar_format.txt |
| MEME format | FOXO1.H12INVIVO.0.PS.A_meme_format.meme |
| Transfac format | FOXO1.H12INVIVO.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 82.0 | 428.0 | 337.0 | 155.0 |
| 02 | 57.0 | 428.0 | 260.0 | 257.0 |
| 03 | 5.0 | 12.0 | 7.0 | 978.0 |
| 04 | 42.0 | 9.0 | 944.0 | 7.0 |
| 05 | 2.0 | 34.0 | 5.0 | 961.0 |
| 06 | 3.0 | 3.0 | 66.0 | 930.0 |
| 07 | 9.0 | 11.0 | 316.0 | 666.0 |
| 08 | 703.0 | 130.0 | 32.0 | 137.0 |
| 09 | 8.0 | 786.0 | 41.0 | 167.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.082 | 0.427 | 0.336 | 0.155 |
| 02 | 0.057 | 0.427 | 0.259 | 0.256 |
| 03 | 0.005 | 0.012 | 0.007 | 0.976 |
| 04 | 0.042 | 0.009 | 0.942 | 0.007 |
| 05 | 0.002 | 0.034 | 0.005 | 0.959 |
| 06 | 0.003 | 0.003 | 0.066 | 0.928 |
| 07 | 0.009 | 0.011 | 0.315 | 0.665 |
| 08 | 0.702 | 0.13 | 0.032 | 0.137 |
| 09 | 0.008 | 0.784 | 0.041 | 0.167 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.103 | 0.533 | 0.295 | -0.476 |
| 02 | -1.457 | 0.533 | 0.037 | 0.025 |
| 03 | -3.624 | -2.911 | -3.364 | 1.357 |
| 04 | -1.752 | -3.158 | 1.322 | -3.364 |
| 05 | -4.215 | -1.954 | -3.624 | 1.339 |
| 06 | -3.977 | -3.977 | -1.315 | 1.307 |
| 07 | -3.158 | -2.987 | 0.231 | 0.974 |
| 08 | 1.027 | -0.65 | -2.012 | -0.598 |
| 09 | -3.255 | 1.139 | -1.775 | -0.402 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.761965 |
| 0.0005 | 5.72601 |
| 0.0001 | 7.40861 |