| Motif | FOXO1.H12INVITRO.0.PS.A |
| Gene (human) | FOXO1 (GeneCards) |
| Gene synonyms (human) | FKHR, FOXO1A |
| Gene (mouse) | Foxo1 |
| Gene synonyms (mouse) | Fkhr, Foxo1a |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | FOXO1.H12INVITRO.0.PS.A |
| Gene (human) | FOXO1 (GeneCards) |
| Gene synonyms (human) | FKHR, FOXO1A |
| Gene (mouse) | Foxo1 |
| Gene synonyms (mouse) | Fkhr, Foxo1a |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 9 |
| Consensus | bTGTTTWCn |
| GC content | 36.54% |
| Information content (bits; total / per base) | 9.633 / 1.07 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 999 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 3 (20) | 0.813 | 0.85 | 0.694 | 0.747 | 0.857 | 0.889 | 2.854 | 3.066 | 77.613 | 132.824 |
| Mouse | 12 (78) | 0.69 | 0.864 | 0.6 | 0.767 | 0.723 | 0.898 | 2.329 | 3.273 | 62.253 | 378.367 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.669 | 0.639 | 0.6 | 0.586 | 0.554 | 0.554 |
| best | 0.699 | 0.668 | 0.615 | 0.603 | 0.561 | 0.563 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.652 | 0.31 | 0.539 | 0.351 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | FOX {3.3.1} (TFClass) |
| TF subfamily | FOXO {3.3.1.15} (TFClass) |
| TFClass ID | TFClass: 3.3.1.15.1 |
| HGNC | HGNC:3819 |
| MGI | MGI:1890077 |
| EntrezGene (human) | GeneID:2308 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:56458 (SSTAR profile) |
| UniProt ID (human) | FOXO1_HUMAN |
| UniProt ID (mouse) | FOXO1_MOUSE |
| UniProt AC (human) | Q12778 (TFClass) |
| UniProt AC (mouse) | Q9R1E0 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 12 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | FOXO1.H12INVITRO.0.PS.A.pcm |
| PWM | FOXO1.H12INVITRO.0.PS.A.pwm |
| PFM | FOXO1.H12INVITRO.0.PS.A.pfm |
| Alignment | FOXO1.H12INVITRO.0.PS.A.words.tsv |
| Threshold to P-value map | FOXO1.H12INVITRO.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | FOXO1.H12INVITRO.0.PS.A_jaspar_format.txt |
| MEME format | FOXO1.H12INVITRO.0.PS.A_meme_format.meme |
| Transfac format | FOXO1.H12INVITRO.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 61.0 | 354.0 | 232.0 | 352.0 |
| 02 | 12.0 | 2.0 | 3.0 | 982.0 |
| 03 | 44.0 | 14.0 | 919.0 | 22.0 |
| 04 | 3.0 | 7.0 | 9.0 | 980.0 |
| 05 | 2.0 | 4.0 | 73.0 | 920.0 |
| 06 | 3.0 | 9.0 | 219.0 | 768.0 |
| 07 | 597.0 | 166.0 | 35.0 | 201.0 |
| 08 | 10.0 | 754.0 | 25.0 | 210.0 |
| 09 | 302.0 | 292.0 | 168.0 | 237.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.061 | 0.354 | 0.232 | 0.352 |
| 02 | 0.012 | 0.002 | 0.003 | 0.983 |
| 03 | 0.044 | 0.014 | 0.92 | 0.022 |
| 04 | 0.003 | 0.007 | 0.009 | 0.981 |
| 05 | 0.002 | 0.004 | 0.073 | 0.921 |
| 06 | 0.003 | 0.009 | 0.219 | 0.769 |
| 07 | 0.598 | 0.166 | 0.035 | 0.201 |
| 08 | 0.01 | 0.755 | 0.025 | 0.21 |
| 09 | 0.302 | 0.292 | 0.168 | 0.237 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.389 | 0.347 | -0.073 | 0.341 |
| 02 | -2.908 | -4.212 | -3.974 | 1.364 |
| 03 | -1.705 | -2.772 | 1.298 | -2.361 |
| 04 | -3.974 | -3.361 | -3.155 | 1.362 |
| 05 | -4.212 | -3.782 | -1.214 | 1.299 |
| 06 | -3.974 | -3.155 | -0.13 | 1.119 |
| 07 | 0.867 | -0.405 | -1.924 | -0.215 |
| 08 | -3.065 | 1.1 | -2.242 | -0.172 |
| 09 | 0.189 | 0.155 | -0.393 | -0.052 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.74332 |
| 0.0005 | 5.910945 |
| 0.0001 | 7.633735 |