FOXL1.H12CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXL1.H12CORE.0.S.B
Gene (human)	FOXL1 (GeneCards)
Gene synonyms (human)	FKHL11, FREAC7
Gene (mouse)	Foxl1
Gene synonyms (mouse)	Fkh6, Fkhl11
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	20
Consensus	bndTRTTTGTTTAYWWdhnn
GC content	26.87%
Information content (bits; total / per base)	17.812 / 0.891
Data sources	HT-SELEX
Aligned words	7137

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.993	0.99	0.911	0.917	0.711	0.764
Non-Methyl HT-SELEX, 2 experiments	best	0.999	0.999	0.99	0.988	0.782	0.832

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXL {3.3.1.12} (TFClass)
TFClass ID	TFClass: 3.3.1.12.1
HGNC	HGNC:3817
MGI	MGI:1347469
EntrezGene (human)	GeneID:2300 (SSTAR profile)
EntrezGene (mouse)	GeneID:14241 (SSTAR profile)
UniProt ID (human)	FOXL1_HUMAN
UniProt ID (mouse)	FOXL1_MOUSE
UniProt AC (human)	Q12952 (TFClass)
UniProt AC (mouse)	Q64731 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	FOXL1.H12CORE.0.S.B.pcm
PWM	FOXL1.H12CORE.0.S.B.pwm
PFM	FOXL1.H12CORE.0.S.B.pfm
Alignment	FOXL1.H12CORE.0.S.B.words.tsv
Threshold to P-value map	FOXL1.H12CORE.0.S.B.thr
Motif in other formats
JASPAR format	FOXL1.H12CORE.0.S.B_jaspar_format.txt
MEME format	FOXL1.H12CORE.0.S.B_meme_format.meme
Transfac format	FOXL1.H12CORE.0.S.B_transfac_format.txt
Homer format	FOXL1.H12CORE.0.S.B_homer_format_0.001.txt FOXL1.H12CORE.0.S.B_homer_format_0.0005.txt FOXL1.H12CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1225.0	1327.0	2811.0	1774.0
02	1486.75	1067.75	2359.75	2222.75
03	1182.0	788.0	2048.0	3119.0
04	278.0	370.0	482.0	6007.0
05	1359.0	422.0	4915.0	441.0
06	641.0	103.0	183.0	6210.0
07	308.0	25.0	39.0	6765.0
08	0.0	1.0	1.0	7135.0
09	2961.0	1.0	4175.0	0.0
10	0.0	19.0	0.0	7118.0
11	9.0	3.0	3.0	7122.0
12	11.0	2.0	171.0	6953.0
13	6521.0	30.0	449.0	137.0
14	279.0	2599.0	88.0	4171.0
15	2406.0	496.0	572.0	3663.0
16	1377.0	555.0	500.0	4705.0
17	2538.0	522.0	547.0	3530.0
18	1211.0	2296.0	760.0	2870.0
19	1542.5	2436.5	1204.5	1953.5
20	1377.0	2704.0	1284.0	1772.0

PFM

	A	C	G	T
01	0.172	0.186	0.394	0.249
02	0.208	0.15	0.331	0.311
03	0.166	0.11	0.287	0.437
04	0.039	0.052	0.068	0.842
05	0.19	0.059	0.689	0.062
06	0.09	0.014	0.026	0.87
07	0.043	0.004	0.005	0.948
08	0.0	0.0	0.0	1.0
09	0.415	0.0	0.585	0.0
10	0.0	0.003	0.0	0.997
11	0.001	0.0	0.0	0.998
12	0.002	0.0	0.024	0.974
13	0.914	0.004	0.063	0.019
14	0.039	0.364	0.012	0.584
15	0.337	0.069	0.08	0.513
16	0.193	0.078	0.07	0.659
17	0.356	0.073	0.077	0.495
18	0.17	0.322	0.106	0.402
19	0.216	0.341	0.169	0.274
20	0.193	0.379	0.18	0.248

PWM

	A	C	G	T
01	-0.375	-0.296	0.454	-0.006
02	-0.182	-0.513	0.279	0.22
03	-0.411	-0.816	0.138	0.558
04	-1.852	-1.569	-1.305	1.213
05	-0.272	-1.438	1.013	-1.394
06	-1.022	-2.832	-2.266	1.246
07	-1.751	-4.184	-3.769	1.332
08	-6.691	-6.319	-6.319	1.385
09	0.506	-6.319	0.849	-6.691
10	-6.691	-4.433	-6.691	1.383
11	-5.07	-5.836	-5.836	1.383
12	-4.906	-6.049	-2.333	1.359
13	1.295	-4.015	-1.376	-2.552
14	-1.849	0.376	-2.986	0.848
15	0.299	-1.277	-1.135	0.719
16	-0.259	-1.165	-1.269	0.969
17	0.352	-1.226	-1.179	0.682
18	-0.387	0.252	-0.852	0.475
19	-0.145	0.311	-0.392	0.091
20	-0.259	0.415	-0.329	-0.007

Standard thresholds

P-value	Threshold
0.001	0.19491
0.0005	1.83511
0.0001	5.20296