FOXK1.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXK1.H12INVIVO.0.PS.A
Gene (human)	FOXK1 (GeneCards)
Gene synonyms (human)	MNF
Gene (mouse)	Foxk1
Gene synonyms (mouse)	Mnf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	10
Consensus	bnTGTTTWYn
GC content	37.54%
Information content (bits; total / per base)	9.689 / 0.969
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1007

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.746	0.785	0.631	0.683	0.759	0.811	2.536	2.848	205.036	260.337
Mouse	2 (14)	0.683	0.843	0.578	0.735	0.758	0.886	2.314	3.277	84.883	257.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.982	0.97	0.97	0.953	0.936	0.914
Non-Methyl HT-SELEX, 1 experiments	best	0.982	0.97	0.97	0.953	0.936	0.914

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.588	0.262	0.687	0.454

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXK {3.3.1.11} (TFClass)
TFClass ID	TFClass: 3.3.1.11.1
HGNC	HGNC:23480
MGI	MGI:1347488
EntrezGene (human)	GeneID:221937 (SSTAR profile)
EntrezGene (mouse)	GeneID:17425 (SSTAR profile)
UniProt ID (human)	FOXK1_HUMAN
UniProt ID (mouse)	FOXK1_MOUSE
UniProt AC (human)	P85037 (TFClass)
UniProt AC (mouse)	P42128 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	FOXK1.H12INVIVO.0.PS.A.pcm
PWM	FOXK1.H12INVIVO.0.PS.A.pwm
PFM	FOXK1.H12INVIVO.0.PS.A.pfm
Alignment	FOXK1.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	FOXK1.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	FOXK1.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	FOXK1.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	FOXK1.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	FOXK1.H12INVIVO.0.PS.A_homer_format_0.001.txt FOXK1.H12INVIVO.0.PS.A_homer_format_0.0005.txt FOXK1.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	83.0	428.0	292.0	204.0
02	146.0	275.0	225.0	361.0
03	21.0	4.0	8.0	974.0
04	83.0	11.0	909.0	4.0
05	8.0	5.0	9.0	985.0
06	5.0	4.0	36.0	962.0
07	4.0	4.0	280.0	719.0
08	671.0	144.0	15.0	177.0
09	2.0	687.0	49.0	269.0
10	379.0	201.0	194.0	233.0

PFM

	A	C	G	T
01	0.082	0.425	0.29	0.203
02	0.145	0.273	0.223	0.358
03	0.021	0.004	0.008	0.967
04	0.082	0.011	0.903	0.004
05	0.008	0.005	0.009	0.978
06	0.005	0.004	0.036	0.955
07	0.004	0.004	0.278	0.714
08	0.666	0.143	0.015	0.176
09	0.002	0.682	0.049	0.267
10	0.376	0.2	0.193	0.231

PWM

	A	C	G	T
01	-1.096	0.528	0.147	-0.209
02	-0.54	0.088	-0.112	0.358
03	-2.412	-3.79	-3.26	1.348
04	-1.096	-2.991	1.279	-3.79
05	-3.26	-3.629	-3.162	1.359
06	-3.629	-3.79	-1.905	1.336
07	-3.79	-3.79	0.106	1.045
08	0.976	-0.554	-2.718	-0.349
09	-4.219	1.0	-1.609	0.066
10	0.407	-0.223	-0.259	-0.077

Standard thresholds

P-value	Threshold
0.001	4.801195
0.0005	5.873445
0.0001	7.56163