FOXJ3.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXJ3.H12CORE.0.SM.B
Gene (human)	FOXJ3 (GeneCards)
Gene synonyms (human)	KIAA1041
Gene (mouse)	Foxj3
Gene synonyms (mouse)	Kiaa1041
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	ndTGTTTACRbn
GC content	34.24%
Information content (bits; total / per base)	13.49 / 1.124
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	7305

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.896	0.879	0.821	0.817	0.771	0.772
Overall, 4 experiments	best	0.997	0.995	0.995	0.992	0.989	0.984
Methyl HT-SELEX, 1 experiments	median	0.997	0.995	0.995	0.992	0.989	0.984
Methyl HT-SELEX, 1 experiments	best	0.997	0.995	0.995	0.992	0.989	0.984
Non-Methyl HT-SELEX, 3 experiments	median	0.804	0.777	0.658	0.661	0.576	0.594
Non-Methyl HT-SELEX, 3 experiments	best	0.988	0.981	0.983	0.972	0.966	0.951

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXJ {3.3.1.10} (TFClass)
TFClass ID	TFClass: 3.3.1.10.3
HGNC	HGNC:29178
MGI	MGI:2443432
EntrezGene (human)	GeneID:22887 (SSTAR profile)
EntrezGene (mouse)	GeneID:230700 (SSTAR profile)
UniProt ID (human)	FOXJ3_HUMAN
UniProt ID (mouse)	FOXJ3_MOUSE
UniProt AC (human)	Q9UPW0 (TFClass)
UniProt AC (mouse)	Q8BUR3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	FOXJ3.H12CORE.0.SM.B.pcm
PWM	FOXJ3.H12CORE.0.SM.B.pwm
PFM	FOXJ3.H12CORE.0.SM.B.pfm
Alignment	FOXJ3.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	FOXJ3.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	FOXJ3.H12CORE.0.SM.B_jaspar_format.txt
MEME format	FOXJ3.H12CORE.0.SM.B_meme_format.meme
Transfac format	FOXJ3.H12CORE.0.SM.B_transfac_format.txt
Homer format	FOXJ3.H12CORE.0.SM.B_homer_format_0.001.txt FOXJ3.H12CORE.0.SM.B_homer_format_0.0005.txt FOXJ3.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1770.0	1250.0	1629.0	2656.0
02	1673.0	852.0	872.0	3908.0
03	0.0	305.0	0.0	7000.0
04	36.0	0.0	7269.0	0.0
05	0.0	0.0	0.0	7305.0
06	0.0	0.0	0.0	7305.0
07	0.0	0.0	1004.0	6301.0
08	7053.0	1.0	251.0	0.0
09	0.0	5726.0	13.0	1566.0
10	949.0	859.0	4802.0	695.0
11	654.5	1563.5	817.5	4269.5
12	1880.0	1410.0	1393.0	2622.0

PFM

	A	C	G	T
01	0.242	0.171	0.223	0.364
02	0.229	0.117	0.119	0.535
03	0.0	0.042	0.0	0.958
04	0.005	0.0	0.995	0.0
05	0.0	0.0	0.0	1.0
06	0.0	0.0	0.0	1.0
07	0.0	0.0	0.137	0.863
08	0.966	0.0	0.034	0.0
09	0.0	0.784	0.002	0.214
10	0.13	0.118	0.657	0.095
11	0.09	0.214	0.112	0.584
12	0.257	0.193	0.191	0.359

PWM

	A	C	G	T
01	-0.031	-0.379	-0.114	0.374
02	-0.088	-0.761	-0.738	0.76
03	-6.712	-1.784	-6.712	1.343
04	-3.868	-6.712	1.38	-6.712
05	-6.712	-6.712	-6.712	1.385
06	-6.712	-6.712	-6.712	1.385
07	-6.712	-6.712	-0.597	1.238
08	1.35	-6.341	-1.977	-6.712
09	-6.712	1.142	-4.788	-0.154
10	-0.653	-0.753	0.966	-0.964
11	-1.024	-0.155	-0.802	0.849
12	0.029	-0.258	-0.27	0.361

Standard thresholds

P-value	Threshold
0.001	1.85342
0.0005	3.716935
0.0001	7.24703