FOXJ2.H12INVIVO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXJ2.H12INVIVO.1.SM.B
Gene (human)	FOXJ2 (GeneCards)
Gene synonyms (human)	FHX
Gene (mouse)	Foxj2
Gene synonyms (mouse)	Fhx
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	14
Consensus	hTRTTTACAACAdh
GC content	24.33%
Information content (bits; total / per base)	19.827 / 1.416
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9950

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.588	0.597	0.41	0.432	0.621	0.655	1.547	1.682	12.833	18.027

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.967	0.955	0.906	0.886	0.801	0.79
Overall, 6 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.992	0.989	0.968	0.961	0.916	0.911
Methyl HT-SELEX, 2 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
Non-Methyl HT-SELEX, 4 experiments	median	0.919	0.891	0.833	0.804	0.718	0.712
Non-Methyl HT-SELEX, 4 experiments	best	1.0	1.0	1.0	1.0	0.969	0.971

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.717	0.469	0.738	0.523

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXJ {3.3.1.10} (TFClass)
TFClass ID	TFClass: 3.3.1.10.2
HGNC	HGNC:24818
MGI	MGI:1926805
EntrezGene (human)	GeneID:55810 (SSTAR profile)
EntrezGene (mouse)	GeneID:60611 (SSTAR profile)
UniProt ID (human)	FOXJ2_HUMAN
UniProt ID (mouse)	FOXJ2_MOUSE
UniProt AC (human)	Q9P0K8 (TFClass)
UniProt AC (mouse)	Q9ES18 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	FOXJ2.H12INVIVO.1.SM.B.pcm
PWM	FOXJ2.H12INVIVO.1.SM.B.pwm
PFM	FOXJ2.H12INVIVO.1.SM.B.pfm
Alignment	FOXJ2.H12INVIVO.1.SM.B.words.tsv
Threshold to P-value map	FOXJ2.H12INVIVO.1.SM.B.thr
Motif in other formats
JASPAR format	FOXJ2.H12INVIVO.1.SM.B_jaspar_format.txt
MEME format	FOXJ2.H12INVIVO.1.SM.B_meme_format.meme
Transfac format	FOXJ2.H12INVIVO.1.SM.B_transfac_format.txt
Homer format	FOXJ2.H12INVIVO.1.SM.B_homer_format_0.001.txt FOXJ2.H12INVIVO.1.SM.B_homer_format_0.0005.txt FOXJ2.H12INVIVO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2188.0	2307.0	1321.0	4134.0
02	58.25	64.25	58.25	9769.25
03	4185.0	60.0	5657.0	48.0
04	40.0	22.0	38.0	9850.0
05	84.0	53.0	12.0	9801.0
06	117.0	5.0	167.0	9661.0
07	9948.0	0.0	0.0	2.0
08	0.0	9945.0	0.0	5.0
09	9892.0	17.0	26.0	15.0
10	9829.0	43.0	23.0	55.0
11	126.0	8251.0	40.0	1533.0
12	9732.0	97.0	54.0	67.0
13	5932.25	1151.25	1242.25	1624.25
14	3754.5	2080.5	1160.5	2954.5

PFM

	A	C	G	T
01	0.22	0.232	0.133	0.415
02	0.006	0.006	0.006	0.982
03	0.421	0.006	0.569	0.005
04	0.004	0.002	0.004	0.99
05	0.008	0.005	0.001	0.985
06	0.012	0.001	0.017	0.971
07	1.0	0.0	0.0	0.0
08	0.0	0.999	0.0	0.001
09	0.994	0.002	0.003	0.002
10	0.988	0.004	0.002	0.006
11	0.013	0.829	0.004	0.154
12	0.978	0.01	0.005	0.007
13	0.596	0.116	0.125	0.163
14	0.377	0.209	0.117	0.297

PWM

	A	C	G	T
01	-0.128	-0.075	-0.632	0.508
02	-3.716	-3.622	-3.716	1.367
03	0.52	-3.688	0.821	-3.902
04	-4.075	-4.629	-4.124	1.376
05	-3.362	-3.807	-5.16	1.371
06	-3.038	-5.832	-2.688	1.356
07	1.385	-6.986	-6.986	-6.361
08	-6.986	1.385	-6.986	-5.832
09	1.38	-4.86	-4.477	-4.969
10	1.373	-4.007	-4.589	-3.772
11	-2.966	1.198	-4.075	-0.483
12	1.363	-3.222	-3.789	-3.581
13	0.869	-0.769	-0.693	-0.426
14	0.411	-0.178	-0.761	0.172

Standard thresholds

P-value	Threshold
0.001	-2.63034
0.0005	-0.90709
0.0001	3.168215