FOXI1.H12RSNP.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXI1.H12RSNP.0.SM.B
Gene (human)	FOXI1 (GeneCards)
Gene synonyms (human)	FKHL10, FREAC6
Gene (mouse)	Foxi1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	nbnWTGTTTACdbWWhvn
GC content	32.75%
Information content (bits; total / per base)	16.928 / 0.94
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	785

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.997	0.995	0.995	0.991	0.98	0.974
Overall, 2 experiments	best	0.999	0.998	0.996	0.994	0.984	0.98
Methyl HT-SELEX, 1 experiments	median	0.999	0.998	0.996	0.994	0.984	0.98
Methyl HT-SELEX, 1 experiments	best	0.999	0.998	0.996	0.994	0.984	0.98
Non-Methyl HT-SELEX, 1 experiments	median	0.996	0.993	0.993	0.988	0.977	0.969
Non-Methyl HT-SELEX, 1 experiments	best	0.996	0.993	0.993	0.988	0.977	0.969

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.75	0.469	0.566	0.414

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXI {3.3.1.9} (TFClass)
TFClass ID	TFClass: 3.3.1.9.1
HGNC	HGNC:3815
MGI	MGI:1096329
EntrezGene (human)	GeneID:2299 (SSTAR profile)
EntrezGene (mouse)	GeneID:14233 (SSTAR profile)
UniProt ID (human)	FOXI1_HUMAN
UniProt ID (mouse)	FOXI1_MOUSE
UniProt AC (human)	Q12951 (TFClass)
UniProt AC (mouse)	Q922I5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	FOXI1.H12RSNP.0.SM.B.pcm
PWM	FOXI1.H12RSNP.0.SM.B.pwm
PFM	FOXI1.H12RSNP.0.SM.B.pfm
Alignment	FOXI1.H12RSNP.0.SM.B.words.tsv
Threshold to P-value map	FOXI1.H12RSNP.0.SM.B.thr
Motif in other formats
JASPAR format	FOXI1.H12RSNP.0.SM.B_jaspar_format.txt
MEME format	FOXI1.H12RSNP.0.SM.B_meme_format.meme
Transfac format	FOXI1.H12RSNP.0.SM.B_transfac_format.txt
Homer format	FOXI1.H12RSNP.0.SM.B_homer_format_0.001.txt FOXI1.H12RSNP.0.SM.B_homer_format_0.0005.txt FOXI1.H12RSNP.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	153.0	175.0	190.0	267.0
02	68.5	238.5	233.5	244.5
03	222.0	116.0	159.0	288.0
04	135.0	75.0	28.0	547.0
05	0.0	2.0	0.0	783.0
06	0.0	0.0	785.0	0.0
07	0.0	0.0	0.0	785.0
08	0.0	0.0	0.0	785.0
09	0.0	0.0	1.0	784.0
10	785.0	0.0	0.0	0.0
11	0.0	708.0	0.0	77.0
12	282.0	44.0	346.0	113.0
13	25.0	121.0	257.0	382.0
14	120.0	48.0	45.0	572.0
15	365.0	56.0	48.0	316.0
16	424.0	108.0	55.0	198.0
17	331.0	220.0	121.0	113.0
18	171.0	307.0	140.0	167.0

PFM

	A	C	G	T
01	0.195	0.223	0.242	0.34
02	0.087	0.304	0.297	0.311
03	0.283	0.148	0.203	0.367
04	0.172	0.096	0.036	0.697
05	0.0	0.003	0.0	0.997
06	0.0	0.0	1.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.0	1.0
09	0.0	0.0	0.001	0.999
10	1.0	0.0	0.0	0.0
11	0.0	0.902	0.0	0.098
12	0.359	0.056	0.441	0.144
13	0.032	0.154	0.327	0.487
14	0.153	0.061	0.057	0.729
15	0.465	0.071	0.061	0.403
16	0.54	0.138	0.07	0.252
17	0.422	0.28	0.154	0.144
18	0.218	0.391	0.178	0.213

PWM

	A	C	G	T
01	-0.247	-0.114	-0.032	0.306
02	-1.037	0.193	0.172	0.218
03	0.122	-0.52	-0.209	0.381
04	-0.37	-0.948	-1.898	1.02
05	-4.777	-3.989	-4.777	1.377
06	-4.777	-4.777	1.38	-4.777
07	-4.777	-4.777	-4.777	1.38
08	-4.777	-4.777	-4.777	1.38
09	-4.777	-4.777	-4.307	1.379
10	1.38	-4.777	-4.777	-4.777
11	-4.777	1.277	-4.777	-0.923
12	0.36	-1.466	0.563	-0.546
13	-2.004	-0.478	0.268	0.662
14	-0.487	-1.383	-1.445	1.064
15	0.617	-1.233	-1.383	0.473
16	0.766	-0.59	-1.251	0.009
17	0.519	0.113	-0.478	-0.546
18	-0.136	0.444	-0.334	-0.16

Standard thresholds

P-value	Threshold
0.001	0.71086
0.0005	2.30521
0.0001	5.43666