FOXI1.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXI1.H12INVITRO.0.SM.B
Gene (human)	FOXI1 (GeneCards)
Gene synonyms (human)	FKHL10, FREAC6
Gene (mouse)	Foxi1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	ndTGTTTACdbhh
GC content	32.07%
Information content (bits; total / per base)	13.646 / 1.05
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9649

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.998	0.996	0.995	0.993	0.985	0.98
Overall, 2 experiments	best	0.999	0.998	0.997	0.995	0.987	0.984
Methyl HT-SELEX, 1 experiments	median	0.999	0.998	0.997	0.995	0.987	0.984
Methyl HT-SELEX, 1 experiments	best	0.999	0.998	0.997	0.995	0.987	0.984
Non-Methyl HT-SELEX, 1 experiments	median	0.997	0.994	0.994	0.99	0.982	0.976
Non-Methyl HT-SELEX, 1 experiments	best	0.997	0.994	0.994	0.99	0.982	0.976

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.724	0.449	0.568	0.373

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXI {3.3.1.9} (TFClass)
TFClass ID	TFClass: 3.3.1.9.1
HGNC	HGNC:3815
MGI	MGI:1096329
EntrezGene (human)	GeneID:2299 (SSTAR profile)
EntrezGene (mouse)	GeneID:14233 (SSTAR profile)
UniProt ID (human)	FOXI1_HUMAN
UniProt ID (mouse)	FOXI1_MOUSE
UniProt AC (human)	Q12951 (TFClass)
UniProt AC (mouse)	Q922I5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	FOXI1.H12INVITRO.0.SM.B.pcm
PWM	FOXI1.H12INVITRO.0.SM.B.pwm
PFM	FOXI1.H12INVITRO.0.SM.B.pfm
Alignment	FOXI1.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	FOXI1.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	FOXI1.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	FOXI1.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	FOXI1.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	FOXI1.H12INVITRO.0.SM.B_homer_format_0.001.txt FOXI1.H12INVITRO.0.SM.B_homer_format_0.0005.txt FOXI1.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2268.25	2199.25	2516.25	2665.25
02	2541.5	1355.5	1440.5	4311.5
03	7.0	11.0	4.0	9627.0
04	160.0	0.0	9489.0	0.0
05	1.0	0.0	0.0	9648.0
06	1.0	0.0	3.0	9645.0
07	1.0	0.0	385.0	9263.0
08	9501.0	11.0	121.0	16.0
09	3.0	8176.0	107.0	1363.0
10	3911.0	1196.0	3156.0	1386.0
11	1062.0	2330.0	2458.0	3799.0
12	2478.5	1323.5	985.5	4861.5
13	3579.0	1701.0	1253.0	3116.0

PFM

	A	C	G	T
01	0.235	0.228	0.261	0.276
02	0.263	0.14	0.149	0.447
03	0.001	0.001	0.0	0.998
04	0.017	0.0	0.983	0.0
05	0.0	0.0	0.0	1.0
06	0.0	0.0	0.0	1.0
07	0.0	0.0	0.04	0.96
08	0.985	0.001	0.013	0.002
09	0.0	0.847	0.011	0.141
10	0.405	0.124	0.327	0.144
11	0.11	0.241	0.255	0.394
12	0.257	0.137	0.102	0.504
13	0.371	0.176	0.13	0.323

PWM

	A	C	G	T
01	-0.061	-0.092	0.042	0.1
02	0.052	-0.576	-0.515	0.58
03	-5.56	-5.202	-5.95	1.383
04	-2.7	-6.959	1.369	-6.959
05	-6.597	-6.959	-6.959	1.385
06	-6.597	-6.959	-6.123	1.385
07	-6.597	-6.959	-1.83	1.345
08	1.37	-5.202	-2.975	-4.883
09	-6.123	1.22	-3.095	-0.57
10	0.483	-0.701	0.269	-0.553
11	-0.819	-0.035	0.019	0.454
12	0.027	-0.599	-0.894	0.7
13	0.394	-0.349	-0.654	0.256

Standard thresholds

P-value	Threshold
0.001	1.736365
0.0005	3.27791
0.0001	6.997975