FOXI1.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXI1.H12CORE.0.SM.B
Gene (human)	FOXI1 (GeneCards)
Gene synonyms (human)	FKHL10, FREAC6
Gene (mouse)	Foxi1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	nbnWTGTTTACdbWWhvh
GC content	32.81%
Information content (bits; total / per base)	17.106 / 0.95
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2006

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.998	0.996	0.995	0.992	0.98	0.975
Overall, 2 experiments	best	0.999	0.998	0.997	0.995	0.984	0.98
Methyl HT-SELEX, 1 experiments	median	0.999	0.998	0.997	0.995	0.984	0.98
Methyl HT-SELEX, 1 experiments	best	0.999	0.998	0.997	0.995	0.984	0.98
Non-Methyl HT-SELEX, 1 experiments	median	0.997	0.994	0.993	0.99	0.976	0.969
Non-Methyl HT-SELEX, 1 experiments	best	0.997	0.994	0.993	0.99	0.976	0.969

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.724	0.495	0.571	0.4

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXI {3.3.1.9} (TFClass)
TFClass ID	TFClass: 3.3.1.9.1
HGNC	HGNC:3815
MGI	MGI:1096329
EntrezGene (human)	GeneID:2299 (SSTAR profile)
EntrezGene (mouse)	GeneID:14233 (SSTAR profile)
UniProt ID (human)	FOXI1_HUMAN
UniProt ID (mouse)	FOXI1_MOUSE
UniProt AC (human)	Q12951 (TFClass)
UniProt AC (mouse)	Q922I5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	FOXI1.H12CORE.0.SM.B.pcm
PWM	FOXI1.H12CORE.0.SM.B.pwm
PFM	FOXI1.H12CORE.0.SM.B.pfm
Alignment	FOXI1.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	FOXI1.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	FOXI1.H12CORE.0.SM.B_jaspar_format.txt
MEME format	FOXI1.H12CORE.0.SM.B_meme_format.meme
Transfac format	FOXI1.H12CORE.0.SM.B_transfac_format.txt
Homer format	FOXI1.H12CORE.0.SM.B_homer_format_0.001.txt FOXI1.H12CORE.0.SM.B_homer_format_0.0005.txt FOXI1.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	402.75	466.75	477.75	658.75
02	200.0	723.0	508.0	575.0
03	626.0	286.0	431.0	663.0
04	443.0	199.0	58.0	1306.0
05	1.0	6.0	0.0	1999.0
06	3.0	0.0	2003.0	0.0
07	0.0	0.0	0.0	2006.0
08	0.0	0.0	0.0	2006.0
09	0.0	0.0	0.0	2006.0
10	2006.0	0.0	0.0	0.0
11	0.0	1909.0	0.0	97.0
12	879.0	66.0	714.0	347.0
13	98.0	226.0	811.0	871.0
14	347.0	136.0	93.0	1430.0
15	1083.0	167.0	95.0	661.0
16	1091.0	338.0	160.0	417.0
17	937.5	500.5	317.5	250.5
18	407.75	840.75	314.75	442.75

PFM

	A	C	G	T
01	0.201	0.233	0.238	0.328
02	0.1	0.36	0.253	0.287
03	0.312	0.143	0.215	0.331
04	0.221	0.099	0.029	0.651
05	0.0	0.003	0.0	0.997
06	0.001	0.0	0.999	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.0	1.0
09	0.0	0.0	0.0	1.0
10	1.0	0.0	0.0	0.0
11	0.0	0.952	0.0	0.048
12	0.438	0.033	0.356	0.173
13	0.049	0.113	0.404	0.434
14	0.173	0.068	0.046	0.713
15	0.54	0.083	0.047	0.33
16	0.544	0.168	0.08	0.208
17	0.467	0.25	0.158	0.125
18	0.203	0.419	0.157	0.221

PWM

	A	C	G	T
01	-0.218	-0.072	-0.048	0.272
02	-0.914	0.365	0.013	0.136
03	0.221	-0.559	-0.151	0.278
04	-0.124	-0.919	-2.129	0.955
05	-5.156	-4.154	-5.579	1.38
06	-4.632	-5.579	1.382	-5.579
07	-5.579	-5.579	-5.579	1.383
08	-5.579	-5.579	-5.579	1.383
09	-5.579	-5.579	-5.579	1.383
10	1.383	-5.579	-5.579	-5.579
11	-5.579	1.334	-5.579	-1.627
12	0.56	-2.003	0.352	-0.367
13	-1.617	-0.792	0.479	0.55
14	-0.367	-1.295	-1.669	1.045
15	0.768	-1.092	-1.648	0.275
16	0.775	-0.393	-1.134	-0.184
17	0.624	-0.002	-0.455	-0.69
18	-0.206	0.515	-0.464	-0.124

Standard thresholds

P-value	Threshold
0.001	-0.33399
0.0005	1.45571
0.0001	4.86551