MotifFOXG1.H12INVIVO.0.PSM.A
Gene (human)FOXG1
(GeneCards)
Gene synonyms (human)FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C
Gene (mouse)Foxg1
Gene synonyms (mouse)Fkhl1, Foxg1b, Hfhbf1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length15
ConsensusbbbTGTTTdYhhdvh
GC content41.4%
Information content (bits; total / per base)9.953 / 0.664
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words1007

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (17) 0.777 0.825 0.63 0.675 0.797 0.852 2.368 2.728 139.119 210.319

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.82 0.758 0.77 0.712 0.704 0.664
best 0.901 0.854 0.863 0.81 0.808 0.76
Methyl HT-SELEX, 1 experiments median 0.901 0.854 0.863 0.81 0.808 0.76
best 0.901 0.854 0.863 0.81 0.808 0.76
Non-Methyl HT-SELEX, 2 experiments median 0.687 0.647 0.653 0.618 0.612 0.59
best 0.82 0.758 0.77 0.712 0.704 0.664
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXG {3.3.1.7} (TFClass)
TFClass IDTFClass: 3.3.1.7.1
HGNCHGNC:3811
MGIMGI:1347464
EntrezGene (human)GeneID:2290
(SSTAR profile)
EntrezGene (mouse)GeneID:15228
(SSTAR profile)
UniProt ID (human)FOXG1_HUMAN
UniProt ID (mouse)FOXG1_MOUSE
UniProt AC (human)P55316
(TFClass)
UniProt AC (mouse)Q60987
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
01115.0341.0257.0294.0
02134.0192.0224.0457.0
03110.0253.0353.0291.0
047.00.01.0999.0
0533.01.0973.00.0
060.07.02.0998.0
071.07.083.0916.0
082.07.0203.0795.0
09343.083.0308.0273.0
1027.0579.0173.0228.0
11484.0223.087.0213.0
12182.0385.0162.0278.0
13445.0148.0182.0232.0
14225.0405.0216.0161.0
15390.0256.0143.0218.0
PFM
ACGT
010.1140.3390.2550.292
020.1330.1910.2220.454
030.1090.2510.3510.289
040.0070.00.0010.992
050.0330.0010.9660.0
060.00.0070.0020.991
070.0010.0070.0820.91
080.0020.0070.2020.789
090.3410.0820.3060.271
100.0270.5750.1720.226
110.4810.2210.0860.212
120.1810.3820.1610.276
130.4420.1470.1810.23
140.2230.4020.2140.16
150.3870.2540.1420.216
PWM
ACGT
01-0.7750.3020.0210.154
02-0.625-0.269-0.1160.593
03-0.8190.0050.3360.144
04-3.369-4.988-4.5311.373
05-1.988-4.5311.347-4.988
06-4.988-3.369-4.2191.372
07-4.531-3.369-1.0961.287
08-4.219-3.369-0.2141.145
090.307-1.0960.20.081
10-2.1770.829-0.372-0.098
110.65-0.12-1.05-0.166
12-0.3220.422-0.4370.099
130.567-0.526-0.322-0.081
14-0.1120.473-0.152-0.443
150.4350.017-0.56-0.143
Standard thresholds
P-value Threshold
0.001 4.95716
0.0005 5.92401
0.0001 7.48981