| Motif | FOXG1.H12CORE.0.PSM.A |
| Gene (human) | FOXG1 (GeneCards) |
| Gene synonyms (human) | FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C |
| Gene (mouse) | Foxg1 |
| Gene synonyms (mouse) | Fkhl1, Foxg1b, Hfhbf1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 15 |
| Consensus | bbbTGTTTdYhhdvh |
| GC content | 41.4% |
| Information content (bits; total / per base) | 9.953 / 0.664 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 1007 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 3 (17) | 0.777 | 0.825 | 0.63 | 0.675 | 0.797 | 0.852 | 2.368 | 2.728 | 139.119 | 210.319 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 3 experiments | median | 0.82 | 0.758 | 0.77 | 0.712 | 0.704 | 0.664 |
| best | 0.901 | 0.854 | 0.863 | 0.81 | 0.808 | 0.76 | |
| Methyl HT-SELEX, 1 experiments | median | 0.901 | 0.854 | 0.863 | 0.81 | 0.808 | 0.76 |
| best | 0.901 | 0.854 | 0.863 | 0.81 | 0.808 | 0.76 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.687 | 0.647 | 0.653 | 0.618 | 0.612 | 0.59 |
| best | 0.82 | 0.758 | 0.77 | 0.712 | 0.704 | 0.664 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | FOX {3.3.1} (TFClass) |
| TF subfamily | FOXG {3.3.1.7} (TFClass) |
| TFClass ID | TFClass: 3.3.1.7.1 |
| HGNC | HGNC:3811 |
| MGI | MGI:1347464 |
| EntrezGene (human) | GeneID:2290 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15228 (SSTAR profile) |
| UniProt ID (human) | FOXG1_HUMAN |
| UniProt ID (mouse) | FOXG1_MOUSE |
| UniProt AC (human) | P55316 (TFClass) |
| UniProt AC (mouse) | Q60987 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 3 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 1 |
| PCM | FOXG1.H12CORE.0.PSM.A.pcm |
| PWM | FOXG1.H12CORE.0.PSM.A.pwm |
| PFM | FOXG1.H12CORE.0.PSM.A.pfm |
| Alignment | FOXG1.H12CORE.0.PSM.A.words.tsv |
| Threshold to P-value map | FOXG1.H12CORE.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | FOXG1.H12CORE.0.PSM.A_jaspar_format.txt |
| MEME format | FOXG1.H12CORE.0.PSM.A_meme_format.meme |
| Transfac format | FOXG1.H12CORE.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 115.0 | 341.0 | 257.0 | 294.0 |
| 02 | 134.0 | 192.0 | 224.0 | 457.0 |
| 03 | 110.0 | 253.0 | 353.0 | 291.0 |
| 04 | 7.0 | 0.0 | 1.0 | 999.0 |
| 05 | 33.0 | 1.0 | 973.0 | 0.0 |
| 06 | 0.0 | 7.0 | 2.0 | 998.0 |
| 07 | 1.0 | 7.0 | 83.0 | 916.0 |
| 08 | 2.0 | 7.0 | 203.0 | 795.0 |
| 09 | 343.0 | 83.0 | 308.0 | 273.0 |
| 10 | 27.0 | 579.0 | 173.0 | 228.0 |
| 11 | 484.0 | 223.0 | 87.0 | 213.0 |
| 12 | 182.0 | 385.0 | 162.0 | 278.0 |
| 13 | 445.0 | 148.0 | 182.0 | 232.0 |
| 14 | 225.0 | 405.0 | 216.0 | 161.0 |
| 15 | 390.0 | 256.0 | 143.0 | 218.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.114 | 0.339 | 0.255 | 0.292 |
| 02 | 0.133 | 0.191 | 0.222 | 0.454 |
| 03 | 0.109 | 0.251 | 0.351 | 0.289 |
| 04 | 0.007 | 0.0 | 0.001 | 0.992 |
| 05 | 0.033 | 0.001 | 0.966 | 0.0 |
| 06 | 0.0 | 0.007 | 0.002 | 0.991 |
| 07 | 0.001 | 0.007 | 0.082 | 0.91 |
| 08 | 0.002 | 0.007 | 0.202 | 0.789 |
| 09 | 0.341 | 0.082 | 0.306 | 0.271 |
| 10 | 0.027 | 0.575 | 0.172 | 0.226 |
| 11 | 0.481 | 0.221 | 0.086 | 0.212 |
| 12 | 0.181 | 0.382 | 0.161 | 0.276 |
| 13 | 0.442 | 0.147 | 0.181 | 0.23 |
| 14 | 0.223 | 0.402 | 0.214 | 0.16 |
| 15 | 0.387 | 0.254 | 0.142 | 0.216 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.775 | 0.302 | 0.021 | 0.154 |
| 02 | -0.625 | -0.269 | -0.116 | 0.593 |
| 03 | -0.819 | 0.005 | 0.336 | 0.144 |
| 04 | -3.369 | -4.988 | -4.531 | 1.373 |
| 05 | -1.988 | -4.531 | 1.347 | -4.988 |
| 06 | -4.988 | -3.369 | -4.219 | 1.372 |
| 07 | -4.531 | -3.369 | -1.096 | 1.287 |
| 08 | -4.219 | -3.369 | -0.214 | 1.145 |
| 09 | 0.307 | -1.096 | 0.2 | 0.081 |
| 10 | -2.177 | 0.829 | -0.372 | -0.098 |
| 11 | 0.65 | -0.12 | -1.05 | -0.166 |
| 12 | -0.322 | 0.422 | -0.437 | 0.099 |
| 13 | 0.567 | -0.526 | -0.322 | -0.081 |
| 14 | -0.112 | 0.473 | -0.152 | -0.443 |
| 15 | 0.435 | 0.017 | -0.56 | -0.143 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.95716 |
| 0.0005 | 5.92401 |
| 0.0001 | 7.48981 |