MotifFOXE1.H12INVIVO.1.S.D
Gene (human)FOXE1
(GeneCards)
Gene synonyms (human)FKHL15, FOXE2, TITF2, TTF2
Gene (mouse)Foxe1
Gene synonyms (mouse)Titf2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length11
ConsensusdbdTTGTTWdn
GC content28.57%
Information content (bits; total / per base)11.613 / 1.056
Data sourcesHT-SELEX
Aligned words6146

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.937 0.897 0.882 0.844 0.795 0.769
best 0.942 0.898 0.908 0.866 0.85 0.809
Methyl HT-SELEX, 1 experiments median 0.932 0.895 0.856 0.822 0.739 0.729
best 0.932 0.895 0.856 0.822 0.739 0.729
Non-Methyl HT-SELEX, 1 experiments median 0.942 0.898 0.908 0.866 0.85 0.809
best 0.942 0.898 0.908 0.866 0.85 0.809

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.708 0.438 0.643 0.486
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXE {3.3.1.5} (TFClass)
TFClass IDTFClass: 3.3.1.5.1
HGNCHGNC:3806
MGIMGI:1353500
EntrezGene (human)GeneID:2304
(SSTAR profile)
EntrezGene (mouse)GeneID:110805
(SSTAR profile)
UniProt ID (human)FOXE1_HUMAN
UniProt ID (mouse)FOXE1_MOUSE
UniProt AC (human)O00358
(TFClass)
UniProt AC (mouse)Q8R2I0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011071.751048.751560.752464.75
02395.251361.251824.252565.25
031365.0623.02498.01660.0
0495.00.015.06036.0
050.00.00.06146.0
060.00.06146.00.0
070.00.00.06146.0
080.00.00.06146.0
091353.00.0317.04476.0
101821.0498.0929.02898.0
111271.01143.01354.02378.0
PFM
ACGT
010.1740.1710.2540.401
020.0640.2210.2970.417
030.2220.1010.4060.27
040.0150.00.0020.982
050.00.00.01.0
060.00.01.00.0
070.00.00.01.0
080.00.00.01.0
090.220.00.0520.728
100.2960.0810.1510.472
110.2070.1860.220.387
PWM
ACGT
01-0.36-0.3810.0160.472
02-1.354-0.1210.1710.512
03-0.118-0.9010.4850.077
04-2.762-6.559-4.4951.367
05-6.559-6.559-6.5591.385
06-6.559-6.5591.385-6.559
07-6.559-6.559-6.5591.385
08-6.559-6.559-6.5591.385
09-0.127-6.559-1.5731.068
100.17-1.124-0.5020.634
11-0.189-0.295-0.1260.436
Standard thresholds
P-value Threshold
0.001 2.743805
0.0005 5.333725
0.0001 7.892175