FOXE1.H12INVITRO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXE1.H12INVITRO.1.S.C
Gene (human)	FOXE1 (GeneCards)
Gene synonyms (human)	FKHL15, FOXE2, TITF2, TTF2
Gene (mouse)	Foxe1
Gene synonyms (mouse)	Titf2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	11
Consensus	nbnWTGTTWdn
GC content	31.87%
Information content (bits; total / per base)	9.536 / 0.867
Data sources	HT-SELEX
Aligned words	9894

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.939	0.896	0.891	0.85	0.809	0.781
Overall, 2 experiments	best	0.946	0.902	0.919	0.877	0.874	0.831
Methyl HT-SELEX, 1 experiments	median	0.932	0.891	0.862	0.824	0.745	0.732
Methyl HT-SELEX, 1 experiments	best	0.932	0.891	0.862	0.824	0.745	0.732
Non-Methyl HT-SELEX, 1 experiments	median	0.946	0.902	0.919	0.877	0.874	0.831
Non-Methyl HT-SELEX, 1 experiments	best	0.946	0.902	0.919	0.877	0.874	0.831

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.686	0.422	0.658	0.508

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXE {3.3.1.5} (TFClass)
TFClass ID	TFClass: 3.3.1.5.1
HGNC	HGNC:3806
MGI	MGI:1353500
EntrezGene (human)	GeneID:2304 (SSTAR profile)
EntrezGene (mouse)	GeneID:110805 (SSTAR profile)
UniProt ID (human)	FOXE1_HUMAN
UniProt ID (mouse)	FOXE1_MOUSE
UniProt AC (human)	O00358 (TFClass)
UniProt AC (mouse)	Q8R2I0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	FOXE1.H12INVITRO.1.S.C.pcm
PWM	FOXE1.H12INVITRO.1.S.C.pwm
PFM	FOXE1.H12INVITRO.1.S.C.pfm
Alignment	FOXE1.H12INVITRO.1.S.C.words.tsv
Threshold to P-value map	FOXE1.H12INVITRO.1.S.C.thr
Motif in other formats
JASPAR format	FOXE1.H12INVITRO.1.S.C_jaspar_format.txt
MEME format	FOXE1.H12INVITRO.1.S.C_meme_format.meme
Transfac format	FOXE1.H12INVITRO.1.S.C_transfac_format.txt
Homer format	FOXE1.H12INVITRO.1.S.C_homer_format_0.001.txt FOXE1.H12INVITRO.1.S.C_homer_format_0.0005.txt FOXE1.H12INVITRO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1932.5	1894.5	2723.5	3343.5
02	882.75	2498.75	2953.75	3558.75
03	2304.0	1447.0	3450.0	2693.0
04	1289.0	420.0	1117.0	7068.0
05	10.0	39.0	18.0	9827.0
06	54.0	5.0	9835.0	0.0
07	5.0	83.0	9.0	9797.0
08	65.0	58.0	75.0	9696.0
09	2408.0	80.0	1148.0	6258.0
10	2946.0	875.0	1626.0	4447.0
11	1807.0	2069.0	2259.0	3759.0

PFM

	A	C	G	T
01	0.195	0.191	0.275	0.338
02	0.089	0.253	0.299	0.36
03	0.233	0.146	0.349	0.272
04	0.13	0.042	0.113	0.714
05	0.001	0.004	0.002	0.993
06	0.005	0.001	0.994	0.0
07	0.001	0.008	0.001	0.99
08	0.007	0.006	0.008	0.98
09	0.243	0.008	0.116	0.633
10	0.298	0.088	0.164	0.449
11	0.183	0.209	0.228	0.38

PWM

	A	C	G	T
01	-0.247	-0.266	0.096	0.301
02	-1.029	0.01	0.177	0.363
03	-0.071	-0.535	0.332	0.085
04	-0.651	-1.769	-0.794	1.049
05	-5.305	-4.093	-4.804	1.379
06	-3.784	-5.826	1.38	-6.981
07	-5.826	-3.368	-5.39	1.376
08	-3.605	-3.715	-3.467	1.365
09	-0.027	-3.404	-0.767	0.928
10	0.175	-1.037	-0.419	0.586
11	-0.314	-0.178	-0.091	0.418

Standard thresholds

P-value	Threshold
0.001	5.214725
0.0005	6.116335
0.0001	7.5244