MotifFOXE1.H12INVITRO.0.SM.B
Gene (human)FOXE1
(GeneCards)
Gene synonyms (human)FKHL15, FOXE2, TITF2, TTF2
Gene (mouse)Foxe1
Gene synonyms (mouse)Titf2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length16
ConsensusnWTGTTKKYWTARbvn
GC content32.85%
Information content (bits; total / per base)14.467 / 0.904
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7750

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.982 0.972 0.951 0.935 0.837 0.833
best 0.995 0.992 0.971 0.965 0.84 0.845
Methyl HT-SELEX, 1 experiments median 0.995 0.992 0.971 0.965 0.835 0.845
best 0.995 0.992 0.971 0.965 0.835 0.845
Non-Methyl HT-SELEX, 1 experiments median 0.97 0.953 0.931 0.906 0.84 0.821
best 0.97 0.953 0.931 0.906 0.84 0.821

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.883 0.741 0.808 0.508
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXE {3.3.1.5} (TFClass)
TFClass IDTFClass: 3.3.1.5.1
HGNCHGNC:3806
MGIMGI:1353500
EntrezGene (human)GeneID:2304
(SSTAR profile)
EntrezGene (mouse)GeneID:110805
(SSTAR profile)
UniProt ID (human)FOXE1_HUMAN
UniProt ID (mouse)FOXE1_MOUSE
UniProt AC (human)O00358
(TFClass)
UniProt AC (mouse)Q8R2I0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012415.251062.252225.252047.25
021158.25432.25959.255200.25
0321.0101.022.07606.0
0470.03.07676.01.0
052.0138.016.07594.0
0613.09.0205.07523.0
072027.02.02165.03556.0
081578.013.01777.04382.0
0930.01170.01165.05385.0
102337.0232.0999.04182.0
1167.0439.0151.07093.0
126077.016.0123.01534.0
133616.054.03833.0247.0
14328.01729.03983.01710.0
151104.751251.754530.75862.75
161533.252050.252197.251969.25
PFM
ACGT
010.3120.1370.2870.264
020.1490.0560.1240.671
030.0030.0130.0030.981
040.0090.00.990.0
050.00.0180.0020.98
060.0020.0010.0260.971
070.2620.00.2790.459
080.2040.0020.2290.565
090.0040.1510.150.695
100.3020.030.1290.54
110.0090.0570.0190.915
120.7840.0020.0160.198
130.4670.0070.4950.032
140.0420.2230.5140.221
150.1430.1620.5850.111
160.1980.2650.2840.254
PWM
ACGT
010.22-0.60.1380.055
02-0.514-1.496-0.7020.987
03-4.424-2.933-4.3821.367
04-3.29-5.9141.376-6.395
05-6.126-2.627-4.6671.365
06-4.846-5.151-2.2361.356
070.045-6.1260.1110.607
08-0.205-4.846-0.0860.815
09-4.097-0.504-0.5081.021
100.187-2.114-0.6610.769
11-3.333-1.481-2.5381.297
121.142-4.667-2.74-0.233
130.623-3.5410.682-2.052
14-1.77-0.1140.72-0.125
15-0.561-0.4360.849-0.808
16-0.2340.0560.1260.016
Standard thresholds
P-value Threshold
0.001 2.59376
0.0005 3.93101
0.0001 6.64516