FOXD3.H12INVIVO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXD3.H12INVIVO.1.S.B
Gene (human)	FOXD3 (GeneCards)
Gene synonyms (human)	HFH2
Gene (mouse)	Foxd3
Gene synonyms (mouse)	Hfh2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	20
Consensus	RhvWWAATATTKACdYWRnn
GC content	23.92%
Information content (bits; total / per base)	18.171 / 0.909
Data sources	HT-SELEX
Aligned words	2389

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.489	0.511	0.325	0.337	0.581	0.62	1.429	1.63	8.155	13.071

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.701	0.707	0.584	0.606	0.538	0.559
Non-Methyl HT-SELEX, 2 experiments	best	0.843	0.856	0.636	0.679	0.555	0.597

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXD {3.3.1.4} (TFClass)
TFClass ID	TFClass: 3.3.1.4.3
HGNC	HGNC:3804
MGI	MGI:1347473
EntrezGene (human)	GeneID:27022 (SSTAR profile)
EntrezGene (mouse)	GeneID:15221 (SSTAR profile)
UniProt ID (human)	FOXD3_HUMAN
UniProt ID (mouse)	FOXD3_MOUSE
UniProt AC (human)	Q9UJU5 (TFClass)
UniProt AC (mouse)	Q61060 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	FOXD3.H12INVIVO.1.S.B.pcm
PWM	FOXD3.H12INVIVO.1.S.B.pwm
PFM	FOXD3.H12INVIVO.1.S.B.pfm
Alignment	FOXD3.H12INVIVO.1.S.B.words.tsv
Threshold to P-value map	FOXD3.H12INVIVO.1.S.B.thr
Motif in other formats
JASPAR format	FOXD3.H12INVIVO.1.S.B_jaspar_format.txt
MEME format	FOXD3.H12INVIVO.1.S.B_meme_format.meme
Transfac format	FOXD3.H12INVIVO.1.S.B_transfac_format.txt
Homer format	FOXD3.H12INVIVO.1.S.B_homer_format_0.001.txt FOXD3.H12INVIVO.1.S.B_homer_format_0.0005.txt FOXD3.H12INVIVO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1436.0	185.0	500.0	268.0
02	900.5	475.5	362.5	650.5
03	1006.0	290.0	1007.0	86.0
04	905.0	196.0	20.0	1268.0
05	1152.0	311.0	29.0	897.0
06	2298.0	13.0	4.0	74.0
07	2293.0	8.0	2.0	86.0
08	5.0	264.0	0.0	2120.0
09	1711.0	3.0	675.0	0.0
10	2.0	3.0	0.0	2384.0
11	17.0	0.0	2.0	2370.0
12	253.0	0.0	294.0	1842.0
13	2048.0	3.0	106.0	232.0
14	6.0	1900.0	97.0	386.0
15	945.0	230.0	252.0	962.0
16	80.0	479.0	29.0	1801.0
17	1559.0	11.0	49.0	770.0
18	1310.0	147.0	752.0	180.0
19	544.25	524.25	883.25	437.25
20	611.25	482.25	840.25	455.25

PFM

	A	C	G	T
01	0.601	0.077	0.209	0.112
02	0.377	0.199	0.152	0.272
03	0.421	0.121	0.422	0.036
04	0.379	0.082	0.008	0.531
05	0.482	0.13	0.012	0.375
06	0.962	0.005	0.002	0.031
07	0.96	0.003	0.001	0.036
08	0.002	0.111	0.0	0.887
09	0.716	0.001	0.283	0.0
10	0.001	0.001	0.0	0.998
11	0.007	0.0	0.001	0.992
12	0.106	0.0	0.123	0.771
13	0.857	0.001	0.044	0.097
14	0.003	0.795	0.041	0.162
15	0.396	0.096	0.105	0.403
16	0.033	0.201	0.012	0.754
17	0.653	0.005	0.021	0.322
18	0.548	0.062	0.315	0.075
19	0.228	0.219	0.37	0.183
20	0.256	0.202	0.352	0.191

PWM

	A	C	G	T
01	0.875	-1.165	-0.177	-0.797
02	0.41	-0.227	-0.497	0.085
03	0.52	-0.719	0.521	-1.919
04	0.414	-1.108	-3.307	0.751
05	0.655	-0.65	-2.963	0.406
06	1.345	-3.691	-4.613	-2.066
07	1.343	-4.099	-5.023	-1.919
08	-4.458	-0.812	-5.731	1.265
09	1.05	-4.797	0.122	-5.731
10	-5.023	-4.797	-5.731	1.382
11	-3.454	-5.731	-5.023	1.376
12	-0.855	-5.731	-0.705	1.124
13	1.23	-4.797	-1.714	-0.941
14	-4.323	1.155	-1.801	-0.435
15	0.458	-0.949	-0.858	0.475
16	-1.99	-0.22	-2.963	1.102
17	0.957	-3.835	-2.465	0.253
18	0.784	-1.392	0.23	-1.192
19	-0.093	-0.13	0.39	-0.311
20	0.023	-0.213	0.34	-0.27

Standard thresholds

P-value	Threshold
0.001	0.43711
0.0005	1.98226
0.0001	5.18471