FOXD3.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXD3.H12INVITRO.1.S.B
Gene (human)	FOXD3 (GeneCards)
Gene synonyms (human)	HFH2
Gene (mouse)	Foxd3
Gene synonyms (mouse)	Hfh2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	20
Consensus	RhRWWAATATTTACdTWRnn
GC content	24.05%
Information content (bits; total / per base)	19.271 / 0.964
Data sources	HT-SELEX
Aligned words	2205

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.513	0.529	0.34	0.345	0.561	0.604	1.373	1.558	8.444	11.377

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.702	0.708	0.588	0.608	0.539	0.56
Non-Methyl HT-SELEX, 2 experiments	best	0.845	0.857	0.643	0.682	0.558	0.6

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXD {3.3.1.4} (TFClass)
TFClass ID	TFClass: 3.3.1.4.3
HGNC	HGNC:3804
MGI	MGI:1347473
EntrezGene (human)	GeneID:27022 (SSTAR profile)
EntrezGene (mouse)	GeneID:15221 (SSTAR profile)
UniProt ID (human)	FOXD3_HUMAN
UniProt ID (mouse)	FOXD3_MOUSE
UniProt AC (human)	Q9UJU5 (TFClass)
UniProt AC (mouse)	Q61060 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	FOXD3.H12INVITRO.1.S.B.pcm
PWM	FOXD3.H12INVITRO.1.S.B.pwm
PFM	FOXD3.H12INVITRO.1.S.B.pfm
Alignment	FOXD3.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	FOXD3.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	FOXD3.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	FOXD3.H12INVITRO.1.S.B_meme_format.meme
Transfac format	FOXD3.H12INVITRO.1.S.B_transfac_format.txt
Homer format	FOXD3.H12INVITRO.1.S.B_homer_format_0.001.txt FOXD3.H12INVITRO.1.S.B_homer_format_0.0005.txt FOXD3.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1373.25	161.25	460.25	210.25
02	847.5	443.5	323.5	590.5
03	957.0	253.0	968.0	27.0
04	840.0	185.0	10.0	1170.0
05	1095.0	293.0	4.0	813.0
06	2167.0	6.0	2.0	30.0
07	2180.0	1.0	2.0	22.0
08	0.0	248.0	0.0	1957.0
09	1620.0	0.0	585.0	0.0
10	0.0	0.0	0.0	2205.0
11	1.0	0.0	0.0	2204.0
12	173.0	0.0	287.0	1745.0
13	1951.0	3.0	82.0	169.0
14	0.0	1830.0	73.0	302.0
15	879.0	215.0	218.0	893.0
16	56.0	460.0	23.0	1666.0
17	1466.0	7.0	44.0	688.0
18	1211.0	122.0	724.0	148.0
19	476.0	490.0	846.0	393.0
20	561.5	433.5	804.5	405.5

PFM

	A	C	G	T
01	0.623	0.073	0.209	0.095
02	0.384	0.201	0.147	0.268
03	0.434	0.115	0.439	0.012
04	0.381	0.084	0.005	0.531
05	0.497	0.133	0.002	0.369
06	0.983	0.003	0.001	0.014
07	0.989	0.0	0.001	0.01
08	0.0	0.112	0.0	0.888
09	0.735	0.0	0.265	0.0
10	0.0	0.0	0.0	1.0
11	0.0	0.0	0.0	1.0
12	0.078	0.0	0.13	0.791
13	0.885	0.001	0.037	0.077
14	0.0	0.83	0.033	0.137
15	0.399	0.098	0.099	0.405
16	0.025	0.209	0.01	0.756
17	0.665	0.003	0.02	0.312
18	0.549	0.055	0.328	0.067
19	0.216	0.222	0.384	0.178
20	0.255	0.197	0.365	0.184

PWM

	A	C	G	T
01	0.911	-1.221	-0.18	-0.958
02	0.429	-0.217	-0.531	0.069
03	0.55	-0.775	0.562	-2.951
04	0.42	-1.085	-3.837	0.751
05	0.685	-0.629	-4.537	0.387
06	1.366	-4.246	-4.948	-2.852
07	1.372	-5.243	-4.948	-3.141
08	-5.661	-0.795	-5.661	1.264
09	1.076	-5.661	0.059	-5.661
10	-5.661	-5.661	-5.661	1.384
11	-5.243	-5.661	-5.661	1.383
12	-1.151	-5.661	-0.65	1.15
13	1.261	-4.721	-1.886	-1.174
14	-5.661	1.197	-1.999	-0.599
15	0.465	-0.936	-0.922	0.481
16	-2.257	-0.18	-3.1	1.104
17	0.976	-4.127	-2.489	0.221
18	0.785	-1.496	0.272	-1.306
19	-0.146	-0.117	0.427	-0.337
20	0.018	-0.239	0.377	-0.306

Standard thresholds

P-value	Threshold
0.001	-0.95934
0.0005	0.76191
0.0001	4.33506