FOXD2.H12RSNP.0.S.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXD2.H12RSNP.0.S.D
Gene (human)	FOXD2 (GeneCards)
Gene synonyms (human)	FKHL17, FREAC9
Gene (mouse)	Foxd2
Gene synonyms (mouse)	Mf2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	20
Consensus	dnRWWAATATTWWYdTWdbn
GC content	27.62%
Information content (bits; total / per base)	18.326 / 0.916
Data sources	HT-SELEX
Aligned words	9070

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.983	0.979	0.907	0.889	0.758	0.774
Overall, 4 experiments	best	0.999	0.999	0.993	0.991	0.947	0.935
Methyl HT-SELEX, 1 experiments	median	0.919	0.892	0.83	0.8	0.718	0.709
Methyl HT-SELEX, 1 experiments	best	0.919	0.892	0.83	0.8	0.718	0.709
Non-Methyl HT-SELEX, 3 experiments	median	0.994	0.99	0.985	0.978	0.798	0.839
Non-Methyl HT-SELEX, 3 experiments	best	0.999	0.999	0.993	0.991	0.947	0.935

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXD {3.3.1.4} (TFClass)
TFClass ID	TFClass: 3.3.1.4.2
HGNC	HGNC:3803
MGI	MGI:1347471
EntrezGene (human)	GeneID:2306 (SSTAR profile)
EntrezGene (mouse)	GeneID:17301 (SSTAR profile)
UniProt ID (human)	FOXD2_HUMAN
UniProt ID (mouse)	FOXD2_MOUSE
UniProt AC (human)	O60548 (TFClass)
UniProt AC (mouse)	O35392 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	FOXD2.H12RSNP.0.S.D.pcm
PWM	FOXD2.H12RSNP.0.S.D.pwm
PFM	FOXD2.H12RSNP.0.S.D.pfm
Alignment	FOXD2.H12RSNP.0.S.D.words.tsv
Threshold to P-value map	FOXD2.H12RSNP.0.S.D.thr
Motif in other formats
JASPAR format	FOXD2.H12RSNP.0.S.D_jaspar_format.txt
MEME format	FOXD2.H12RSNP.0.S.D_meme_format.meme
Transfac format	FOXD2.H12RSNP.0.S.D_transfac_format.txt
Homer format	FOXD2.H12RSNP.0.S.D_homer_format_0.001.txt FOXD2.H12RSNP.0.S.D_homer_format_0.0005.txt FOXD2.H12RSNP.0.S.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3152.0	969.0	3731.0	1218.0
02	2385.75	1630.75	2717.75	2335.75
03	2346.0	355.0	6250.0	119.0
04	2092.0	563.0	144.0	6271.0
05	5622.0	1457.0	35.0	1956.0
06	8942.0	34.0	9.0	85.0
07	8887.0	24.0	1.0	158.0
08	1.0	1796.0	0.0	7273.0
09	5515.0	0.0	3555.0	0.0
10	0.0	0.0	0.0	9070.0
11	1.0	0.0	0.0	9069.0
12	1320.0	0.0	803.0	6947.0
13	6582.0	18.0	1030.0	1440.0
14	1.0	5396.0	391.0	3282.0
15	1976.0	1005.0	1146.0	4943.0
16	81.0	932.0	51.0	8006.0
17	5427.0	26.0	119.0	3498.0
18	3718.0	1258.0	2598.0	1496.0
19	832.5	4514.5	2210.5	1512.5
20	1791.0	3328.0	2004.0	1947.0

PFM

	A	C	G	T
01	0.348	0.107	0.411	0.134
02	0.263	0.18	0.3	0.258
03	0.259	0.039	0.689	0.013
04	0.231	0.062	0.016	0.691
05	0.62	0.161	0.004	0.216
06	0.986	0.004	0.001	0.009
07	0.98	0.003	0.0	0.017
08	0.0	0.198	0.0	0.802
09	0.608	0.0	0.392	0.0
10	0.0	0.0	0.0	1.0
11	0.0	0.0	0.0	1.0
12	0.146	0.0	0.089	0.766
13	0.726	0.002	0.114	0.159
14	0.0	0.595	0.043	0.362
15	0.218	0.111	0.126	0.545
16	0.009	0.103	0.006	0.883
17	0.598	0.003	0.013	0.386
18	0.41	0.139	0.286	0.165
19	0.092	0.498	0.244	0.167
20	0.197	0.367	0.221	0.215

PWM

	A	C	G	T
01	0.329	-0.849	0.498	-0.621
02	0.051	-0.329	0.181	0.03
03	0.034	-1.849	1.013	-2.929
04	-0.08	-1.39	-2.742	1.017
05	0.907	-0.442	-4.109	-0.148
06	1.371	-4.136	-5.305	-3.258
07	1.365	-4.459	-6.54	-2.651
08	-6.54	-0.233	-6.904	1.165
09	0.888	-6.904	0.449	-6.904
10	-6.904	-6.904	-6.904	1.386
11	-6.54	-6.904	-6.904	1.385
12	-0.54	-6.904	-1.036	1.119
13	1.065	-4.718	-0.788	-0.453
14	-6.54	0.866	-1.753	0.369
15	-0.137	-0.812	-0.681	0.779
16	-3.305	-0.888	-3.752	1.261
17	0.872	-4.385	-2.929	0.433
18	0.494	-0.588	0.136	-0.415
19	-1.0	0.688	-0.025	-0.404
20	-0.236	0.383	-0.123	-0.152

Standard thresholds

P-value	Threshold
0.001	-1.09809
0.0005	0.75266
0.0001	4.53711