MotifFOXD2.H12INVITRO.0.S.B
Gene (human)FOXD2
(GeneCards)
Gene synonyms (human)FKHL17, FREAC9
Gene (mouse)Foxd2
Gene synonyms (mouse)Mf2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length20
ConsensusdnRWWAATATTWWYdTWdbn
GC content27.62%
Information content (bits; total / per base)18.326 / 0.916
Data sourcesHT-SELEX
Aligned words9070

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.983 0.979 0.907 0.889 0.758 0.774
best 0.999 0.999 0.993 0.991 0.947 0.935
Methyl HT-SELEX, 1 experiments median 0.919 0.892 0.83 0.8 0.718 0.709
best 0.919 0.892 0.83 0.8 0.718 0.709
Non-Methyl HT-SELEX, 3 experiments median 0.994 0.99 0.985 0.978 0.798 0.839
best 0.999 0.999 0.993 0.991 0.947 0.935
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXD {3.3.1.4} (TFClass)
TFClass IDTFClass: 3.3.1.4.2
HGNCHGNC:3803
MGIMGI:1347471
EntrezGene (human)GeneID:2306
(SSTAR profile)
EntrezGene (mouse)GeneID:17301
(SSTAR profile)
UniProt ID (human)FOXD2_HUMAN
UniProt ID (mouse)FOXD2_MOUSE
UniProt AC (human)O60548
(TFClass)
UniProt AC (mouse)O35392
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
013152.0969.03731.01218.0
022385.751630.752717.752335.75
032346.0355.06250.0119.0
042092.0563.0144.06271.0
055622.01457.035.01956.0
068942.034.09.085.0
078887.024.01.0158.0
081.01796.00.07273.0
095515.00.03555.00.0
100.00.00.09070.0
111.00.00.09069.0
121320.00.0803.06947.0
136582.018.01030.01440.0
141.05396.0391.03282.0
151976.01005.01146.04943.0
1681.0932.051.08006.0
175427.026.0119.03498.0
183718.01258.02598.01496.0
19832.54514.52210.51512.5
201791.03328.02004.01947.0
PFM
ACGT
010.3480.1070.4110.134
020.2630.180.30.258
030.2590.0390.6890.013
040.2310.0620.0160.691
050.620.1610.0040.216
060.9860.0040.0010.009
070.980.0030.00.017
080.00.1980.00.802
090.6080.00.3920.0
100.00.00.01.0
110.00.00.01.0
120.1460.00.0890.766
130.7260.0020.1140.159
140.00.5950.0430.362
150.2180.1110.1260.545
160.0090.1030.0060.883
170.5980.0030.0130.386
180.410.1390.2860.165
190.0920.4980.2440.167
200.1970.3670.2210.215
PWM
ACGT
010.329-0.8490.498-0.621
020.051-0.3290.1810.03
030.034-1.8491.013-2.929
04-0.08-1.39-2.7421.017
050.907-0.442-4.109-0.148
061.371-4.136-5.305-3.258
071.365-4.459-6.54-2.651
08-6.54-0.233-6.9041.165
090.888-6.9040.449-6.904
10-6.904-6.904-6.9041.386
11-6.54-6.904-6.9041.385
12-0.54-6.904-1.0361.119
131.065-4.718-0.788-0.453
14-6.540.866-1.7530.369
15-0.137-0.812-0.6810.779
16-3.305-0.888-3.7521.261
170.872-4.385-2.9290.433
180.494-0.5880.136-0.415
19-1.00.688-0.025-0.404
20-0.2360.383-0.123-0.152
Standard thresholds
P-value Threshold
0.001 -1.09809
0.0005 0.75266
0.0001 4.53711