MotifFOXD2.H12CORE.1.SM.B
Gene (human)FOXD2
(GeneCards)
Gene synonyms (human)FKHL17, FREAC9
Gene (mouse)Foxd2
Gene synonyms (mouse)Mf2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length15
ConsensusnTGTTWKYbTWdbbn
GC content32.62%
Information content (bits; total / per base)11.134 / 0.742
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9679

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.971 0.955 0.951 0.928 0.88 0.866
best 0.991 0.986 0.985 0.976 0.972 0.958
Methyl HT-SELEX, 1 experiments median 0.991 0.986 0.985 0.976 0.972 0.958
best 0.991 0.986 0.985 0.976 0.972 0.958
Non-Methyl HT-SELEX, 3 experiments median 0.959 0.935 0.93 0.899 0.806 0.8
best 0.984 0.975 0.972 0.957 0.953 0.932
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXD {3.3.1.4} (TFClass)
TFClass IDTFClass: 3.3.1.4.2
HGNCHGNC:3803
MGIMGI:1347471
EntrezGene (human)GeneID:2306
(SSTAR profile)
EntrezGene (mouse)GeneID:17301
(SSTAR profile)
UniProt ID (human)FOXD2_HUMAN
UniProt ID (mouse)FOXD2_MOUSE
UniProt AC (human)O60548
(TFClass)
UniProt AC (mouse)O35392
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012627.01724.02098.03230.0
0299.25795.2548.258736.25
033788.021.05869.01.0
043.027.023.09626.0
053.07.077.09592.0
066382.01.0881.02415.0
071504.011.02047.06117.0
086.02553.01111.06009.0
091170.01173.04485.02851.0
10316.01098.0407.07858.0
114873.0135.0580.04091.0
124161.0557.03930.01031.0
131136.02119.04399.02025.0
141711.252086.254064.251817.25
152237.251889.253150.252402.25
PFM
ACGT
010.2710.1780.2170.334
020.010.0820.0050.903
030.3910.0020.6060.0
040.00.0030.0020.995
050.00.0010.0080.991
060.6590.00.0910.25
070.1550.0010.2110.632
080.0010.2640.1150.621
090.1210.1210.4630.295
100.0330.1130.0420.812
110.5030.0140.060.423
120.430.0580.4060.107
130.1170.2190.4540.209
140.1770.2160.420.188
150.2310.1950.3250.248
PWM
ACGT
010.082-0.339-0.1430.289
02-3.172-1.111-3.871.283
030.448-4.6440.885-6.6
04-6.126-4.415-4.5621.38
05-6.126-5.563-3.4191.377
060.969-6.6-1.009-0.002
07-0.475-5.205-0.1670.927
08-5.6770.054-0.7770.909
09-0.726-0.7230.6170.164
10-2.029-0.789-1.7781.177
110.7-2.87-1.4250.525
120.542-1.4660.485-0.852
13-0.755-0.1330.597-0.178
14-0.346-0.1480.518-0.286
15-0.078-0.2470.264-0.007
Standard thresholds
P-value Threshold
0.001 4.42546
0.0005 5.49751
0.0001 7.46961