MotifFOXC2.H12INVIVO.0.SM.D
Gene (human)FOXC2
(GeneCards)
Gene synonyms (human)FKHL14, MFH1
Gene (mouse)Foxc2
Gene synonyms (mouse)Fkh14, Fkhl14, Mfh1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length17
ConsensusdndWTGTTTAYhYWnnn
GC content26.6%
Information content (bits; total / per base)14.959 / 0.88
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9237

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.961 0.939 0.944 0.912 0.837 0.834
best 0.992 0.987 0.964 0.955 0.915 0.883
Methyl HT-SELEX, 1 experiments median 0.957 0.928 0.938 0.904 0.889 0.854
best 0.957 0.928 0.938 0.904 0.889 0.854
Non-Methyl HT-SELEX, 3 experiments median 0.965 0.939 0.951 0.921 0.786 0.814
best 0.992 0.987 0.964 0.955 0.915 0.883

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.756 0.501 0.754 0.57
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXC {3.3.1.3} (TFClass)
TFClass IDTFClass: 3.3.1.3.2
HGNCHGNC:3801
MGIMGI:1347481
EntrezGene (human)GeneID:2303
(SSTAR profile)
EntrezGene (mouse)GeneID:14234
(SSTAR profile)
UniProt ID (human)FOXC2_HUMAN
UniProt ID (mouse)FOXC2_MOUSE
UniProt AC (human)Q99958
(TFClass)
UniProt AC (mouse)Q61850
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011770.751265.751404.754795.75
022007.51721.53372.52135.5
033000.0804.0960.04473.0
041774.0419.0537.06507.0
0516.028.013.09180.0
061462.03.07772.00.0
073.02.00.09232.0
082.00.00.09235.0
0910.01.0309.08917.0
108690.012.0477.058.0
1132.05421.083.03701.0
122728.0962.0960.04587.0
13501.01033.0482.07221.0
145006.0247.0518.03466.0
153304.01504.02060.02369.0
161457.252745.252270.252764.25
171854.752454.751934.752992.75
PFM
ACGT
010.1920.1370.1520.519
020.2170.1860.3650.231
030.3250.0870.1040.484
040.1920.0450.0580.704
050.0020.0030.0010.994
060.1580.00.8410.0
070.00.00.00.999
080.00.00.01.0
090.0010.00.0330.965
100.9410.0010.0520.006
110.0030.5870.0090.401
120.2950.1040.1040.497
130.0540.1120.0520.782
140.5420.0270.0560.375
150.3580.1630.2230.256
160.1580.2970.2460.299
170.2010.2660.2090.324
PWM
ACGT
01-0.265-0.6-0.4960.73
02-0.14-0.2930.378-0.078
030.261-1.053-0.8760.661
04-0.263-1.702-1.4551.035
05-4.84-4.335-5.0191.379
06-0.457-6.0811.213-6.92
07-6.081-6.291-6.921.385
08-6.291-6.92-6.921.385
09-5.237-6.557-2.0051.35
101.325-5.087-1.573-3.647
11-4.2110.853-3.30.471
120.166-0.874-0.8760.686
13-1.525-0.803-1.5631.139
140.773-2.227-1.4910.406
150.358-0.428-0.1140.026
16-0.460.173-0.0170.18
17-0.2190.061-0.1770.259
Standard thresholds
P-value Threshold
0.001 1.73891
0.0005 3.30456
0.0001 6.49591