MotifFOXC1.H12INVIVO.1.S.D
Gene (human)FOXC1
(GeneCards)
Gene synonyms (human)FKHL7, FREAC3
Gene (mouse)Foxc1
Gene synonyms (mouse)Fkh1, Fkhl7, Freac3, Mf1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length14
ConsensushhhWTRTTTAYhYh
GC content28.78%
Information content (bits; total / per base)11.525 / 0.823
Data sourcesHT-SELEX
Aligned words1061

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.799 0.781 0.668 0.67 0.586 0.602
best 0.92 0.901 0.744 0.75 0.622 0.649
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXC {3.3.1.3} (TFClass)
TFClass IDTFClass: 3.3.1.3.1
HGNCHGNC:3800
MGIMGI:1347466
EntrezGene (human)GeneID:2296
(SSTAR profile)
EntrezGene (mouse)GeneID:17300
(SSTAR profile)
UniProt ID (human)FOXC1_HUMAN
UniProt ID (mouse)FOXC1_MOUSE
UniProt AC (human)Q12948
(TFClass)
UniProt AC (mouse)Q61572
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01214.5261.5117.5467.5
02173.5438.5169.5279.5
03385.0280.066.0330.0
04344.065.068.0584.0
051.0119.00.0941.0
06340.092.0629.00.0
070.030.00.01031.0
080.00.00.01061.0
090.099.00.0962.0
10896.070.043.052.0
114.0700.09.0348.0
12175.0198.0163.0525.0
1362.0276.088.0635.0
14385.0149.0144.0383.0
PFM
ACGT
010.2020.2460.1110.441
020.1640.4130.160.263
030.3630.2640.0620.311
040.3240.0610.0640.55
050.0010.1120.00.887
060.320.0870.5930.0
070.00.0280.00.972
080.00.00.01.0
090.00.0930.00.907
100.8440.0660.0410.049
110.0040.660.0080.328
120.1650.1870.1540.495
130.0580.260.0830.598
140.3630.140.1360.361
PWM
ACGT
01-0.211-0.014-0.8060.564
02-0.4210.5-0.4440.052
030.3710.054-1.3720.217
040.258-1.386-1.3420.786
05-4.579-0.794-5.0321.262
060.247-1.0470.86-5.032
07-5.032-2.13-5.0321.353
08-5.032-5.032-5.0321.381
09-5.032-0.975-5.0321.284
101.213-1.314-1.786-1.603
11-3.8390.966-3.2130.27
12-0.413-0.29-0.4830.679
13-1.4320.039-1.090.869
140.371-0.572-0.6050.365
Standard thresholds
P-value Threshold
0.001 4.35221
0.0005 5.40401
0.0001 7.39801