| Motif | FOXC1.H12INVITRO.1.S.C |
| Gene (human) | FOXC1 (GeneCards) |
| Gene synonyms (human) | FKHL7, FREAC3 |
| Gene (mouse) | Foxc1 |
| Gene synonyms (mouse) | Fkh1, Fkhl7, Freac3, Mf1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | C |
| Motif | FOXC1.H12INVITRO.1.S.C |
| Gene (human) | FOXC1 (GeneCards) |
| Gene synonyms (human) | FKHL7, FREAC3 |
| Gene (mouse) | Foxc1 |
| Gene synonyms (mouse) | Fkh1, Fkhl7, Freac3, Mf1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | C |
| Motif length | 14 |
| Consensus | hhhWTRTTTAYhYh |
| GC content | 28.78% |
| Information content (bits; total / per base) | 11.525 / 0.823 |
| Data sources | HT-SELEX |
| Aligned words | 1061 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.799 | 0.781 | 0.668 | 0.67 | 0.586 | 0.602 |
| best | 0.92 | 0.901 | 0.744 | 0.75 | 0.622 | 0.649 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | FOX {3.3.1} (TFClass) |
| TF subfamily | FOXC {3.3.1.3} (TFClass) |
| TFClass ID | TFClass: 3.3.1.3.1 |
| HGNC | HGNC:3800 |
| MGI | MGI:1347466 |
| EntrezGene (human) | GeneID:2296 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17300 (SSTAR profile) |
| UniProt ID (human) | FOXC1_HUMAN |
| UniProt ID (mouse) | FOXC1_MOUSE |
| UniProt AC (human) | Q12948 (TFClass) |
| UniProt AC (mouse) | Q61572 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | FOXC1.H12INVITRO.1.S.C.pcm |
| PWM | FOXC1.H12INVITRO.1.S.C.pwm |
| PFM | FOXC1.H12INVITRO.1.S.C.pfm |
| Alignment | FOXC1.H12INVITRO.1.S.C.words.tsv |
| Threshold to P-value map | FOXC1.H12INVITRO.1.S.C.thr |
| Motif in other formats | |
| JASPAR format | FOXC1.H12INVITRO.1.S.C_jaspar_format.txt |
| MEME format | FOXC1.H12INVITRO.1.S.C_meme_format.meme |
| Transfac format | FOXC1.H12INVITRO.1.S.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 214.5 | 261.5 | 117.5 | 467.5 |
| 02 | 173.5 | 438.5 | 169.5 | 279.5 |
| 03 | 385.0 | 280.0 | 66.0 | 330.0 |
| 04 | 344.0 | 65.0 | 68.0 | 584.0 |
| 05 | 1.0 | 119.0 | 0.0 | 941.0 |
| 06 | 340.0 | 92.0 | 629.0 | 0.0 |
| 07 | 0.0 | 30.0 | 0.0 | 1031.0 |
| 08 | 0.0 | 0.0 | 0.0 | 1061.0 |
| 09 | 0.0 | 99.0 | 0.0 | 962.0 |
| 10 | 896.0 | 70.0 | 43.0 | 52.0 |
| 11 | 4.0 | 700.0 | 9.0 | 348.0 |
| 12 | 175.0 | 198.0 | 163.0 | 525.0 |
| 13 | 62.0 | 276.0 | 88.0 | 635.0 |
| 14 | 385.0 | 149.0 | 144.0 | 383.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.202 | 0.246 | 0.111 | 0.441 |
| 02 | 0.164 | 0.413 | 0.16 | 0.263 |
| 03 | 0.363 | 0.264 | 0.062 | 0.311 |
| 04 | 0.324 | 0.061 | 0.064 | 0.55 |
| 05 | 0.001 | 0.112 | 0.0 | 0.887 |
| 06 | 0.32 | 0.087 | 0.593 | 0.0 |
| 07 | 0.0 | 0.028 | 0.0 | 0.972 |
| 08 | 0.0 | 0.0 | 0.0 | 1.0 |
| 09 | 0.0 | 0.093 | 0.0 | 0.907 |
| 10 | 0.844 | 0.066 | 0.041 | 0.049 |
| 11 | 0.004 | 0.66 | 0.008 | 0.328 |
| 12 | 0.165 | 0.187 | 0.154 | 0.495 |
| 13 | 0.058 | 0.26 | 0.083 | 0.598 |
| 14 | 0.363 | 0.14 | 0.136 | 0.361 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.211 | -0.014 | -0.806 | 0.564 |
| 02 | -0.421 | 0.5 | -0.444 | 0.052 |
| 03 | 0.371 | 0.054 | -1.372 | 0.217 |
| 04 | 0.258 | -1.386 | -1.342 | 0.786 |
| 05 | -4.579 | -0.794 | -5.032 | 1.262 |
| 06 | 0.247 | -1.047 | 0.86 | -5.032 |
| 07 | -5.032 | -2.13 | -5.032 | 1.353 |
| 08 | -5.032 | -5.032 | -5.032 | 1.381 |
| 09 | -5.032 | -0.975 | -5.032 | 1.284 |
| 10 | 1.213 | -1.314 | -1.786 | -1.603 |
| 11 | -3.839 | 0.966 | -3.213 | 0.27 |
| 12 | -0.413 | -0.29 | -0.483 | 0.679 |
| 13 | -1.432 | 0.039 | -1.09 | 0.869 |
| 14 | 0.371 | -0.572 | -0.605 | 0.365 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.35221 |
| 0.0005 | 5.40401 |
| 0.0001 | 7.39801 |