MotifFOXC1.H12CORE.0.S.B
Gene (human)FOXC1
(GeneCards)
Gene synonyms (human)FKHL7, FREAC3
Gene (mouse)Foxc1
Gene synonyms (mouse)Fkh1, Fkhl7, Freac3, Mf1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length19
ConsensusndWvWWTATTTAChTWdbn
GC content26.77%
Information content (bits; total / per base)16.399 / 0.863
Data sourcesHT-SELEX
Aligned words8600

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.823 0.818 0.676 0.69 0.579 0.609
best 0.958 0.951 0.765 0.784 0.617 0.662
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXC {3.3.1.3} (TFClass)
TFClass IDTFClass: 3.3.1.3.1
HGNCHGNC:3800
MGIMGI:1347466
EntrezGene (human)GeneID:2296
(SSTAR profile)
EntrezGene (mouse)GeneID:17300
(SSTAR profile)
UniProt ID (human)FOXC1_HUMAN
UniProt ID (mouse)FOXC1_MOUSE
UniProt AC (human)Q12948
(TFClass)
UniProt AC (mouse)Q61572
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
012216.51974.51318.53090.5
022638.51093.53372.51495.5
031429.01106.0484.05581.0
042968.02975.01421.01236.0
055979.0251.0372.01998.0
065841.0180.0172.02407.0
077.018.011.08564.0
085972.08.02619.01.0
091.09.00.08590.0
102.04.03.08591.0
1119.01.01873.06707.0
128288.029.0172.0111.0
1311.07013.066.01510.0
144084.0749.0552.03215.0
15264.01443.0168.06725.0
165300.0137.0295.02868.0
174092.0640.02790.01078.0
181194.252191.253523.251691.25
191936.52059.52653.51950.5
PFM
ACGT
010.2580.230.1530.359
020.3070.1270.3920.174
030.1660.1290.0560.649
040.3450.3460.1650.144
050.6950.0290.0430.232
060.6790.0210.020.28
070.0010.0020.0010.996
080.6940.0010.3050.0
090.00.0010.00.999
100.00.00.00.999
110.0020.00.2180.78
120.9640.0030.020.013
130.0010.8150.0080.176
140.4750.0870.0640.374
150.0310.1680.020.782
160.6160.0160.0340.333
170.4760.0740.3240.125
180.1390.2550.410.197
190.2250.2390.3090.227
PWM
ACGT
010.03-0.085-0.4880.363
020.205-0.6750.45-0.363
03-0.408-0.664-1.4880.953
040.3220.324-0.414-0.553
051.022-2.14-1.749-0.073
060.999-2.469-2.5140.113
07-5.448-4.665-5.0891.381
081.021-5.3460.197-6.491
09-6.491-5.253-6.8571.384
10-6.224-5.839-6.0131.384
11-4.617-6.491-0.1381.137
121.349-4.232-2.514-2.945
13-5.0891.182-3.451-0.353
140.641-1.053-1.3570.402
15-2.09-0.398-2.5371.14
160.902-2.738-1.980.288
170.643-1.2090.26-0.689
18-0.5870.0190.494-0.24
19-0.104-0.0430.21-0.097
Standard thresholds
P-value Threshold
0.001 0.97611
0.0005 2.56461
0.0001 5.81686