FOXC1.H12CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXC1.H12CORE.0.S.B
Gene (human)	FOXC1 (GeneCards)
Gene synonyms (human)	FKHL7, FREAC3
Gene (mouse)	Foxc1
Gene synonyms (mouse)	Fkh1, Fkhl7, Freac3, Mf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	ndWvWWTATTTAChTWdbn
GC content	26.77%
Information content (bits; total / per base)	16.399 / 0.863
Data sources	HT-SELEX
Aligned words	8600

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.823	0.818	0.676	0.69	0.579	0.609
Non-Methyl HT-SELEX, 2 experiments	best	0.958	0.951	0.765	0.784	0.617	0.662

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXC {3.3.1.3} (TFClass)
TFClass ID	TFClass: 3.3.1.3.1
HGNC	HGNC:3800
MGI	MGI:1347466
EntrezGene (human)	GeneID:2296 (SSTAR profile)
EntrezGene (mouse)	GeneID:17300 (SSTAR profile)
UniProt ID (human)	FOXC1_HUMAN
UniProt ID (mouse)	FOXC1_MOUSE
UniProt AC (human)	Q12948 (TFClass)
UniProt AC (mouse)	Q61572 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	FOXC1.H12CORE.0.S.B.pcm
PWM	FOXC1.H12CORE.0.S.B.pwm
PFM	FOXC1.H12CORE.0.S.B.pfm
Alignment	FOXC1.H12CORE.0.S.B.words.tsv
Threshold to P-value map	FOXC1.H12CORE.0.S.B.thr
Motif in other formats
JASPAR format	FOXC1.H12CORE.0.S.B_jaspar_format.txt
MEME format	FOXC1.H12CORE.0.S.B_meme_format.meme
Transfac format	FOXC1.H12CORE.0.S.B_transfac_format.txt
Homer format	FOXC1.H12CORE.0.S.B_homer_format_0.001.txt FOXC1.H12CORE.0.S.B_homer_format_0.0005.txt FOXC1.H12CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2216.5	1974.5	1318.5	3090.5
02	2638.5	1093.5	3372.5	1495.5
03	1429.0	1106.0	484.0	5581.0
04	2968.0	2975.0	1421.0	1236.0
05	5979.0	251.0	372.0	1998.0
06	5841.0	180.0	172.0	2407.0
07	7.0	18.0	11.0	8564.0
08	5972.0	8.0	2619.0	1.0
09	1.0	9.0	0.0	8590.0
10	2.0	4.0	3.0	8591.0
11	19.0	1.0	1873.0	6707.0
12	8288.0	29.0	172.0	111.0
13	11.0	7013.0	66.0	1510.0
14	4084.0	749.0	552.0	3215.0
15	264.0	1443.0	168.0	6725.0
16	5300.0	137.0	295.0	2868.0
17	4092.0	640.0	2790.0	1078.0
18	1194.25	2191.25	3523.25	1691.25
19	1936.5	2059.5	2653.5	1950.5

PFM

	A	C	G	T
01	0.258	0.23	0.153	0.359
02	0.307	0.127	0.392	0.174
03	0.166	0.129	0.056	0.649
04	0.345	0.346	0.165	0.144
05	0.695	0.029	0.043	0.232
06	0.679	0.021	0.02	0.28
07	0.001	0.002	0.001	0.996
08	0.694	0.001	0.305	0.0
09	0.0	0.001	0.0	0.999
10	0.0	0.0	0.0	0.999
11	0.002	0.0	0.218	0.78
12	0.964	0.003	0.02	0.013
13	0.001	0.815	0.008	0.176
14	0.475	0.087	0.064	0.374
15	0.031	0.168	0.02	0.782
16	0.616	0.016	0.034	0.333
17	0.476	0.074	0.324	0.125
18	0.139	0.255	0.41	0.197
19	0.225	0.239	0.309	0.227

PWM

	A	C	G	T
01	0.03	-0.085	-0.488	0.363
02	0.205	-0.675	0.45	-0.363
03	-0.408	-0.664	-1.488	0.953
04	0.322	0.324	-0.414	-0.553
05	1.022	-2.14	-1.749	-0.073
06	0.999	-2.469	-2.514	0.113
07	-5.448	-4.665	-5.089	1.381
08	1.021	-5.346	0.197	-6.491
09	-6.491	-5.253	-6.857	1.384
10	-6.224	-5.839	-6.013	1.384
11	-4.617	-6.491	-0.138	1.137
12	1.349	-4.232	-2.514	-2.945
13	-5.089	1.182	-3.451	-0.353
14	0.641	-1.053	-1.357	0.402
15	-2.09	-0.398	-2.537	1.14
16	0.902	-2.738	-1.98	0.288
17	0.643	-1.209	0.26	-0.689
18	-0.587	0.019	0.494	-0.24
19	-0.104	-0.043	0.21	-0.097

Standard thresholds

P-value	Threshold
0.001	0.97611
0.0005	2.56461
0.0001	5.81686