MotifFOXB1.H12INVIVO.0.SM.D
Gene (human)FOXB1
(GeneCards)
Gene synonyms (human)FKH5
Gene (mouse)Foxb1
Gene synonyms (mouse)Fkh5, Foxb1a, Foxb1b, Mf3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length19
ConsensusnvYMAATATTTACdYWdnn
GC content30.61%
Information content (bits; total / per base)16.771 / 0.883
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7254

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.999 0.998 0.953 0.953 0.746 0.789
best 0.999 0.999 0.987 0.984 0.923 0.92
Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.987 0.984 0.923 0.92
best 0.999 0.998 0.987 0.984 0.923 0.92
Non-Methyl HT-SELEX, 2 experiments median 0.9 0.901 0.8 0.809 0.659 0.692
best 0.999 0.999 0.953 0.953 0.746 0.789

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.926 0.504 0.885 0.634
batch 2 0.668 0.353 0.724 0.522
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyFOX {3.3.1} (TFClass)
TF subfamilyFOXB {3.3.1.2} (TFClass)
TFClass IDTFClass: 3.3.1.2.1
HGNCHGNC:3799
MGIMGI:1927549
EntrezGene (human)GeneID:27023
(SSTAR profile)
EntrezGene (mouse)GeneID:64290
(SSTAR profile)
UniProt ID (human)FOXB1_HUMAN
UniProt ID (mouse)FOXB1_MOUSE
UniProt AC (human)Q99853
(TFClass)
UniProt AC (mouse)Q64732
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
011570.01518.01281.02885.0
021408.51066.53772.51006.5
03348.03046.0385.03475.0
044131.02268.0424.0431.0
056078.0447.0275.0454.0
066494.0237.0144.0379.0
070.093.01.07160.0
086664.00.0590.00.0
090.00.00.07254.0
101.01.012.07240.0
1126.02.01415.05811.0
125069.03.02175.07.0
13234.05843.0164.01013.0
143376.0590.0968.02320.0
15302.02324.0331.04297.0
164692.073.0329.02160.0
172860.0739.02539.01116.0
181074.52368.52394.51416.5
191593.251980.252388.251292.25
PFM
ACGT
010.2160.2090.1770.398
020.1940.1470.520.139
030.0480.420.0530.479
040.5690.3130.0580.059
050.8380.0620.0380.063
060.8950.0330.020.052
070.00.0130.00.987
080.9190.00.0810.0
090.00.00.01.0
100.00.00.0020.998
110.0040.00.1950.801
120.6990.00.30.001
130.0320.8050.0230.14
140.4650.0810.1330.32
150.0420.320.0460.592
160.6470.010.0450.298
170.3940.1020.350.154
180.1480.3270.330.195
190.220.2730.3290.178
PWM
ACGT
01-0.144-0.178-0.3470.464
02-0.252-0.530.732-0.588
03-1.6460.518-1.5450.65
040.8230.223-1.449-1.433
051.209-1.397-1.879-1.381
061.275-2.027-2.519-1.561
07-6.706-2.948-6.3341.372
081.301-6.706-1.12-6.706
09-6.706-6.706-6.7061.385
10-6.334-6.334-4.8491.383
11-4.164-6.064-0.2481.164
121.027-5.8510.182-5.283
13-2.0391.169-2.391-0.581
140.621-1.12-0.6270.246
15-1.7860.248-1.6950.862
160.95-3.184-1.7010.175
170.455-0.8960.336-0.485
18-0.5230.2670.278-0.247
19-0.1290.0880.275-0.338
Standard thresholds
P-value Threshold
0.001 0.98501
0.0005 2.59121
0.0001 5.80371