FOSL2.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOSL2.H12INVITRO.0.P.D
Gene (human)	FOSL2 (GeneCards)
Gene synonyms (human)	FRA2
Gene (mouse)	Fosl2
Gene synonyms (mouse)	Fra-2, Fra2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	12
Consensus	vvRTGAGTCAYh
GC content	48.13%
Information content (bits; total / per base)	14.649 / 1.221
Data sources	ChIP-Seq
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	28 (191)	0.963	0.992	0.918	0.978	0.964	0.987	4.437	5.341	329.569	750.77
Mouse	11 (71)	0.96	0.992	0.921	0.978	0.959	0.991	4.381	5.391	441.495	656.886

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	100.0	4.076	0.357	0.272

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.4
HGNC	HGNC:3798
MGI	MGI:102858
EntrezGene (human)	GeneID:2355 (SSTAR profile)
EntrezGene (mouse)	GeneID:14284 (SSTAR profile)
UniProt ID (human)	FOSL2_HUMAN
UniProt ID (mouse)	FOSL2_MOUSE
UniProt AC (human)	P15408 (TFClass)
UniProt AC (mouse)	P47930 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	28 human, 11 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	FOSL2.H12INVITRO.0.P.D.pcm
PWM	FOSL2.H12INVITRO.0.P.D.pwm
PFM	FOSL2.H12INVITRO.0.P.D.pfm
Alignment	FOSL2.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	FOSL2.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	FOSL2.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	FOSL2.H12INVITRO.0.P.D_meme_format.meme
Transfac format	FOSL2.H12INVITRO.0.P.D_transfac_format.txt
Homer format	FOSL2.H12INVITRO.0.P.D_homer_format_0.001.txt FOSL2.H12INVITRO.0.P.D_homer_format_0.0005.txt FOSL2.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	190.0	211.0	419.0	181.0
02	232.0	176.0	433.0	160.0
03	488.0	152.0	346.0	15.0
04	0.0	3.0	2.0	996.0
05	2.0	1.0	982.0	16.0
06	986.0	6.0	0.0	9.0
07	48.0	0.0	953.0	0.0
08	0.0	1.0	0.0	1000.0
09	5.0	995.0	1.0	0.0
10	998.0	1.0	0.0	2.0
11	10.0	372.0	131.0	488.0
12	164.0	451.0	145.0	241.0

PFM

	A	C	G	T
01	0.19	0.211	0.419	0.181
02	0.232	0.176	0.433	0.16
03	0.488	0.152	0.346	0.015
04	0.0	0.003	0.002	0.995
05	0.002	0.001	0.981	0.016
06	0.985	0.006	0.0	0.009
07	0.048	0.0	0.952	0.0
08	0.0	0.001	0.0	0.999
09	0.005	0.994	0.001	0.0
10	0.997	0.001	0.0	0.002
11	0.01	0.372	0.131	0.488
12	0.164	0.451	0.145	0.241

PWM

	A	C	G	T
01	-0.273	-0.169	0.513	-0.321
02	-0.075	-0.349	0.545	-0.443
03	0.665	-0.494	0.322	-2.712
04	-4.983	-3.976	-4.214	1.376
05	-4.214	-4.526	1.362	-2.654
06	1.366	-3.485	-4.983	-3.157
07	-1.623	-4.983	1.332	-4.983
08	-4.983	-4.526	-4.983	1.38
09	-3.623	1.375	-4.526	-4.983
10	1.378	-4.526	-4.983	-4.214
11	-3.067	0.394	-0.641	0.665
12	-0.419	0.586	-0.541	-0.037

Standard thresholds

P-value	Threshold
0.001	1.95841
0.0005	3.66962
0.0001	6.12323