FOSB.H12RSNP.2.M.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOSB.H12RSNP.2.M.D
Gene (human)	FOSB (GeneCards)
Gene synonyms (human)	G0S3
Gene (mouse)	Fosb
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	D

Motif length	16
Consensus	ndRTKACGTCATCRbn
GC content	47.26%
Information content (bits; total / per base)	17.359 / 1.085
Data sources	Methyl-HT-SELEX
Aligned words	548

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.689	0.695	0.495	0.504	0.523	0.536	1.191	1.225	11.696	14.796
Mouse	4 (27)	0.623	0.666	0.444	0.491	0.499	0.544	1.17	1.274	3.523	6.022

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.916	0.891	0.83	0.801	0.715	0.707
Methyl HT-SELEX, 1 experiments	best	0.916	0.891	0.83	0.801	0.715	0.707

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.2
HGNC	HGNC:3797
MGI	MGI:95575
EntrezGene (human)	GeneID:2354 (SSTAR profile)
EntrezGene (mouse)	GeneID:14282 (SSTAR profile)
UniProt ID (human)	FOSB_HUMAN
UniProt ID (mouse)	FOSB_MOUSE
UniProt AC (human)	P53539 (TFClass)
UniProt AC (mouse)	P13346 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	1

PCM	FOSB.H12RSNP.2.M.D.pcm
PWM	FOSB.H12RSNP.2.M.D.pwm
PFM	FOSB.H12RSNP.2.M.D.pfm
Alignment	FOSB.H12RSNP.2.M.D.words.tsv
Threshold to P-value map	FOSB.H12RSNP.2.M.D.thr
Motif in other formats
JASPAR format	FOSB.H12RSNP.2.M.D_jaspar_format.txt
MEME format	FOSB.H12RSNP.2.M.D_meme_format.meme
Transfac format	FOSB.H12RSNP.2.M.D_transfac_format.txt
Homer format	FOSB.H12RSNP.2.M.D_homer_format_0.001.txt FOSB.H12RSNP.2.M.D_homer_format_0.0005.txt FOSB.H12RSNP.2.M.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	110.0	141.0	147.0	150.0
02	110.25	88.25	224.25	125.25
03	385.0	26.0	111.0	26.0
04	37.0	11.0	24.0	476.0
05	21.0	46.0	409.0	72.0
06	476.0	14.0	57.0	1.0
07	4.0	489.0	2.0	53.0
08	11.0	0.0	537.0	0.0
09	0.0	0.0	0.0	548.0
10	0.0	548.0	0.0	0.0
11	548.0	0.0	0.0	0.0
12	0.0	0.0	0.0	548.0
13	60.0	445.0	20.0	23.0
14	302.0	47.0	191.0	8.0
15	80.0	202.0	81.0	185.0
16	113.5	163.5	119.5	151.5

PFM

	A	C	G	T
01	0.201	0.257	0.268	0.274
02	0.201	0.161	0.409	0.229
03	0.703	0.047	0.203	0.047
04	0.068	0.02	0.044	0.869
05	0.038	0.084	0.746	0.131
06	0.869	0.026	0.104	0.002
07	0.007	0.892	0.004	0.097
08	0.02	0.0	0.98	0.0
09	0.0	0.0	0.0	1.0
10	0.0	1.0	0.0	0.0
11	1.0	0.0	0.0	0.0
12	0.0	0.0	0.0	1.0
13	0.109	0.812	0.036	0.042
14	0.551	0.086	0.349	0.015
15	0.146	0.369	0.148	0.338
16	0.207	0.298	0.218	0.276

PWM

	A	C	G	T
01	-0.217	0.028	0.07	0.09
02	-0.214	-0.434	0.488	-0.089
03	1.026	-1.614	-0.208	-1.614
04	-1.279	-2.4	-1.69	1.237
05	-1.815	-1.069	1.086	-0.633
06	1.237	-2.186	-0.861	-3.985
07	-3.213	1.264	-3.657	-0.932
08	-2.4	-4.476	1.358	-4.476
09	-4.476	-4.476	-4.476	1.378
10	-4.476	1.378	-4.476	-4.476
11	1.378	-4.476	-4.476	-4.476
12	-4.476	-4.476	-4.476	1.378
13	-0.811	1.17	-1.86	-1.73
14	0.784	-1.048	0.329	-2.672
15	-0.53	0.385	-0.518	0.297
16	-0.186	0.175	-0.135	0.1

Standard thresholds

P-value	Threshold
0.001	1.28211
0.0005	2.72556
0.0001	5.72446