FOS.H12RSNP.2.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOS.H12RSNP.2.S.C
Gene (human)	FOS (GeneCards)
Gene synonyms (human)	G0S7
Gene (mouse)	Fos
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	C

Motif length	16
Consensus	nbRTGACGTCATCRhn
GC content	49.19%
Information content (bits; total / per base)	19.324 / 1.208
Data sources	HT-SELEX
Aligned words	285

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	25 (159)	0.553	0.623	0.392	0.456	0.465	0.534	0.998	1.333	0.77	7.155
Mouse	27 (180)	0.579	0.671	0.413	0.553	0.466	0.659	1.031	1.776	2.184	69.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.852	0.824	0.756	0.727	0.672	0.658
Non-Methyl HT-SELEX, 1 experiments	best	0.852	0.824	0.756	0.727	0.672	0.658

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.517	0.016	0.007	0.181

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.1
HGNC	HGNC:3796
MGI	MGI:95574
EntrezGene (human)	GeneID:2353 (SSTAR profile)
EntrezGene (mouse)	GeneID:14281 (SSTAR profile)
UniProt ID (human)	FOS_HUMAN
UniProt ID (mouse)	FOS_MOUSE
UniProt AC (human)	P01100 (TFClass)
UniProt AC (mouse)	P01101 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	25 human, 27 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	FOS.H12RSNP.2.S.C.pcm
PWM	FOS.H12RSNP.2.S.C.pwm
PFM	FOS.H12RSNP.2.S.C.pfm
Alignment	FOS.H12RSNP.2.S.C.words.tsv
Threshold to P-value map	FOS.H12RSNP.2.S.C.thr
Motif in other formats
JASPAR format	FOS.H12RSNP.2.S.C_jaspar_format.txt
MEME format	FOS.H12RSNP.2.S.C_meme_format.meme
Transfac format	FOS.H12RSNP.2.S.C_transfac_format.txt
Homer format	FOS.H12RSNP.2.S.C_homer_format_0.001.txt FOS.H12RSNP.2.S.C_homer_format_0.0005.txt FOS.H12RSNP.2.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	59.0	88.0	75.0	63.0
02	39.25	64.25	118.25	63.25
03	181.0	9.0	92.0	3.0
04	2.0	3.0	7.0	273.0
05	1.0	8.0	253.0	23.0
06	275.0	1.0	8.0	1.0
07	0.0	282.0	0.0	3.0
08	0.0	0.0	285.0	0.0
09	0.0	0.0	0.0	285.0
10	0.0	285.0	0.0	0.0
11	285.0	0.0	0.0	0.0
12	0.0	2.0	1.0	282.0
13	16.0	236.0	11.0	22.0
14	175.0	31.0	63.0	16.0
15	55.5	113.5	38.5	77.5
16	52.75	76.75	91.75	63.75

PFM

	A	C	G	T
01	0.207	0.309	0.263	0.221
02	0.138	0.225	0.415	0.222
03	0.635	0.032	0.323	0.011
04	0.007	0.011	0.025	0.958
05	0.004	0.028	0.888	0.081
06	0.965	0.004	0.028	0.004
07	0.0	0.989	0.0	0.011
08	0.0	0.0	1.0	0.0
09	0.0	0.0	0.0	1.0
10	0.0	1.0	0.0	0.0
11	1.0	0.0	0.0	0.0
12	0.0	0.007	0.004	0.989
13	0.056	0.828	0.039	0.077
14	0.614	0.109	0.221	0.056
15	0.195	0.398	0.135	0.272
16	0.185	0.269	0.322	0.224

PWM

	A	C	G	T
01	-0.185	0.207	0.05	-0.121
02	-0.581	-0.101	0.499	-0.117
03	0.92	-1.943	0.251	-2.801
04	-3.058	-2.801	-2.156	1.329
05	-3.405	-2.044	1.253	-1.091
06	1.336	-3.405	-2.044	-3.405
07	-3.94	1.361	-3.94	-2.801
08	-3.94	-3.94	1.372	-3.94
09	-3.94	-3.94	-3.94	1.372
10	-3.94	1.372	-3.94	-3.94
11	1.372	-3.94	-3.94	-3.94
12	-3.94	-3.058	-3.405	1.361
13	-1.429	1.184	-1.767	-1.133
14	0.887	-0.807	-0.121	-1.429
15	-0.244	0.458	-0.599	0.083
16	-0.294	0.073	0.249	-0.109

Standard thresholds

P-value	Threshold
0.001	0.43801
0.0005	1.89761
0.0001	4.99416