MotifFOS.H12INVIVO.1.S.C
Gene (human)FOS
(GeneCards)
Gene synonyms (human)G0S7
Gene (mouse)Fos
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length10
ConsensusnvYGTCATbn
GC content51.09%
Information content (bits; total / per base)9.492 / 0.949
Data sourcesHT-SELEX
Aligned words8573

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 25 (159) 0.665 0.794 0.458 0.6 0.587 0.689 1.215 1.626 34.102 102.824
Mouse 27 (180) 0.693 0.772 0.486 0.612 0.601 0.684 1.279 1.674 30.208 89.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 1 experiments median 0.898 0.864 0.813 0.779 0.7 0.691
best 0.898 0.864 0.813 0.779 0.7 0.691

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.603 0.017 0.139 0.148
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyFos-related {1.1.2} (TFClass)
TF subfamilyFos {1.1.2.1} (TFClass)
TFClass IDTFClass: 1.1.2.1.1
HGNCHGNC:3796
MGIMGI:95574
EntrezGene (human)GeneID:2353
(SSTAR profile)
EntrezGene (mouse)GeneID:14281
(SSTAR profile)
UniProt ID (human)FOS_HUMAN
UniProt ID (mouse)FOS_MOUSE
UniProt AC (human)P01100
(TFClass)
UniProt AC (mouse)P01101
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 25 human, 27 mouse
HT-SELEX 1
Methyl-HT-SELEX 0
PCM
ACGT
011684.252497.252307.252084.25
022895.251470.253002.251205.25
03371.05350.0611.02241.0
04568.0252.07719.034.0
050.01.00.08572.0
0618.08555.00.00.0
078417.0155.01.00.0
0854.01490.057.06972.0
091175.754253.751450.751692.75
102802.52502.52122.51145.5
PFM
ACGT
010.1960.2910.2690.243
020.3380.1710.350.141
030.0430.6240.0710.261
040.0660.0290.90.004
050.00.00.01.0
060.0020.9980.00.0
070.9820.0180.00.0
080.0060.1740.0070.813
090.1370.4960.1690.197
100.3270.2920.2480.134
PWM
ACGT
01-0.2410.1530.074-0.028
020.3-0.3760.337-0.575
03-1.7490.914-1.2520.045
04-1.325-2.1331.281-4.08
05-6.854-6.488-6.8541.385
06-4.6621.383-6.854-6.854
071.367-2.613-6.488-6.854
08-3.641-0.363-3.5891.179
09-0.60.685-0.39-0.236
100.2680.155-0.01-0.626
Standard thresholds
P-value Threshold
0.001 5.153315
0.0005 6.10106
0.0001 7.583535