FOS.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOS.H12INVIVO.0.P.B
Gene (human)	FOS (GeneCards)
Gene synonyms (human)	G0S7
Gene (mouse)	Fos
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	nnvTGAGTCAb
GC content	46.78%
Information content (bits; total / per base)	13.817 / 1.256
Data sources	ChIP-Seq
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	25 (159)	0.879	0.99	0.843	0.973	0.88	0.993	3.852	5.574	268.42	650.114
Mouse	27 (180)	0.926	0.987	0.888	0.967	0.921	0.984	3.958	4.946	266.054	623.041

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.653	0.616	0.61	0.581	0.577	0.559
Non-Methyl HT-SELEX, 1 experiments	best	0.653	0.616	0.61	0.581	0.577	0.559

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.614	0.019	-0.099	-0.17

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.1
HGNC	HGNC:3796
MGI	MGI:95574
EntrezGene (human)	GeneID:2353 (SSTAR profile)
EntrezGene (mouse)	GeneID:14281 (SSTAR profile)
UniProt ID (human)	FOS_HUMAN
UniProt ID (mouse)	FOS_MOUSE
UniProt AC (human)	P01100 (TFClass)
UniProt AC (mouse)	P01101 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	25 human, 27 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	FOS.H12INVIVO.0.P.B.pcm
PWM	FOS.H12INVIVO.0.P.B.pwm
PFM	FOS.H12INVIVO.0.P.B.pfm
Alignment	FOS.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	FOS.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	FOS.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	FOS.H12INVIVO.0.P.B_meme_format.meme
Transfac format	FOS.H12INVIVO.0.P.B_transfac_format.txt
Homer format	FOS.H12INVIVO.0.P.B_homer_format_0.001.txt FOS.H12INVIVO.0.P.B_homer_format_0.0005.txt FOS.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	182.0	298.0	357.0	164.0
02	278.0	148.0	291.0	284.0
03	386.0	202.0	393.0	20.0
04	5.0	1.0	1.0	994.0
05	1.0	2.0	952.0	46.0
06	989.0	2.0	0.0	10.0
07	0.0	0.0	920.0	81.0
08	1.0	2.0	0.0	998.0
09	14.0	986.0	1.0	0.0
10	999.0	1.0	0.0	1.0
11	20.0	413.0	181.0	387.0

PFM

	A	C	G	T
01	0.182	0.298	0.357	0.164
02	0.278	0.148	0.291	0.284
03	0.386	0.202	0.393	0.02
04	0.005	0.001	0.001	0.993
05	0.001	0.002	0.951	0.046
06	0.988	0.002	0.0	0.01
07	0.0	0.0	0.919	0.081
08	0.001	0.002	0.0	0.997
09	0.014	0.985	0.001	0.0
10	0.998	0.001	0.0	0.001
11	0.02	0.413	0.181	0.387

PWM

	A	C	G	T
01	-0.316	0.174	0.353	-0.419
02	0.104	-0.521	0.15	0.126
03	0.431	-0.213	0.449	-2.451
04	-3.623	-4.526	-4.526	1.374
05	-4.526	-4.214	1.331	-1.664
06	1.369	-4.214	-4.983	-3.067
07	-4.983	-4.983	1.297	-1.114
08	-4.526	-4.214	-4.983	1.378
09	-2.774	1.366	-4.526	-4.983
10	1.379	-4.526	-4.983	-4.526
11	-2.451	0.498	-0.321	0.434

Standard thresholds

P-value	Threshold
0.001	2.64313
0.0005	4.115255
0.0001	6.79777