FOS.H12INVITRO.2.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOS.H12INVITRO.2.S.C
Gene (human)	FOS (GeneCards)
Gene synonyms (human)	G0S7
Gene (mouse)	Fos
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	C

Motif length	14
Consensus	nRTGACGTCATCRn
GC content	47.86%
Information content (bits; total / per base)	18.499 / 1.321
Data sources	HT-SELEX
Aligned words	507

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	25 (159)	0.535	0.588	0.378	0.438	0.486	0.568	1.043	1.318	1.137	8.62
Mouse	27 (180)	0.568	0.659	0.403	0.53	0.483	0.661	1.058	1.757	2.538	68.824

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.866	0.836	0.77	0.74	0.682	0.667
Non-Methyl HT-SELEX, 1 experiments	best	0.866	0.836	0.77	0.74	0.682	0.667

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.473	0.015	-0.077	0.035

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.1
HGNC	HGNC:3796
MGI	MGI:95574
EntrezGene (human)	GeneID:2353 (SSTAR profile)
EntrezGene (mouse)	GeneID:14281 (SSTAR profile)
UniProt ID (human)	FOS_HUMAN
UniProt ID (mouse)	FOS_MOUSE
UniProt AC (human)	P01100 (TFClass)
UniProt AC (mouse)	P01101 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	25 human, 27 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	FOS.H12INVITRO.2.S.C.pcm
PWM	FOS.H12INVITRO.2.S.C.pwm
PFM	FOS.H12INVITRO.2.S.C.pfm
Alignment	FOS.H12INVITRO.2.S.C.words.tsv
Threshold to P-value map	FOS.H12INVITRO.2.S.C.thr
Motif in other formats
JASPAR format	FOS.H12INVITRO.2.S.C_jaspar_format.txt
MEME format	FOS.H12INVITRO.2.S.C_meme_format.meme
Transfac format	FOS.H12INVITRO.2.S.C_transfac_format.txt
Homer format	FOS.H12INVITRO.2.S.C_homer_format_0.001.txt FOS.H12INVITRO.2.S.C_homer_format_0.0005.txt FOS.H12INVITRO.2.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	100.75	115.75	179.75	110.75
02	295.25	18.25	177.25	16.25
03	10.0	4.0	17.0	476.0
04	14.0	25.0	422.0	46.0
05	480.0	1.0	25.0	1.0
06	0.0	500.0	0.0	7.0
07	0.0	0.0	507.0	0.0
08	0.0	0.0	0.0	507.0
09	0.0	507.0	0.0	0.0
10	507.0	0.0	0.0	0.0
11	0.0	2.0	0.0	505.0
12	45.0	420.0	14.0	28.0
13	287.75	52.75	129.75	36.75
14	97.25	174.25	105.25	130.25

PFM

	A	C	G	T
01	0.199	0.228	0.355	0.218
02	0.582	0.036	0.35	0.032
03	0.02	0.008	0.034	0.939
04	0.028	0.049	0.832	0.091
05	0.947	0.002	0.049	0.002
06	0.0	0.986	0.0	0.014
07	0.0	0.0	1.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	1.0	0.0	0.0
10	1.0	0.0	0.0	0.0
11	0.0	0.004	0.0	0.996
12	0.089	0.828	0.028	0.055
13	0.568	0.104	0.256	0.072
14	0.192	0.344	0.208	0.257

PWM

	A	C	G	T
01	-0.226	-0.09	0.346	-0.133
02	0.839	-1.868	0.332	-1.975
03	-2.407	-3.139	-1.934	1.314
04	-2.11	-1.575	1.194	-0.992
05	1.323	-3.916	-1.575	-3.916
06	-4.412	1.363	-4.412	-2.708
07	-4.412	-4.412	1.377	-4.412
08	-4.412	-4.412	-4.412	1.377
09	-4.412	1.377	-4.412	-4.412
10	1.377	-4.412	-4.412	-4.412
11	-4.412	-3.585	-4.412	1.373
12	-1.014	1.19	-2.11	-1.468
13	0.813	-0.86	0.023	-1.209
14	-0.261	0.315	-0.183	0.027

Standard thresholds

P-value	Threshold
0.001	0.27891
0.0005	1.80641
0.0001	5.035065