| Motif | FOS.H12INVITRO.1.S.C |
| Gene (human) | FOS (GeneCards) |
| Gene synonyms (human) | G0S7 |
| Gene (mouse) | Fos |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | C |
| Motif | FOS.H12INVITRO.1.S.C |
| Gene (human) | FOS (GeneCards) |
| Gene synonyms (human) | G0S7 |
| Gene (mouse) | Fos |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | C |
| Motif length | 10 |
| Consensus | nvYGTCATbn |
| GC content | 51.09% |
| Information content (bits; total / per base) | 9.492 / 0.949 |
| Data sources | HT-SELEX |
| Aligned words | 8573 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 25 (159) | 0.665 | 0.794 | 0.458 | 0.6 | 0.587 | 0.689 | 1.215 | 1.626 | 34.102 | 102.824 |
| Mouse | 27 (180) | 0.693 | 0.772 | 0.486 | 0.612 | 0.601 | 0.684 | 1.279 | 1.674 | 30.208 | 89.62 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 1 experiments | median | 0.898 | 0.864 | 0.813 | 0.779 | 0.7 | 0.691 |
| best | 0.898 | 0.864 | 0.813 | 0.779 | 0.7 | 0.691 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.603 | 0.017 | 0.139 | 0.148 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
| TF family | Fos-related {1.1.2} (TFClass) |
| TF subfamily | Fos {1.1.2.1} (TFClass) |
| TFClass ID | TFClass: 1.1.2.1.1 |
| HGNC | HGNC:3796 |
| MGI | MGI:95574 |
| EntrezGene (human) | GeneID:2353 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:14281 (SSTAR profile) |
| UniProt ID (human) | FOS_HUMAN |
| UniProt ID (mouse) | FOS_MOUSE |
| UniProt AC (human) | P01100 (TFClass) |
| UniProt AC (mouse) | P01101 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 25 human, 27 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 0 |
| PCM | FOS.H12INVITRO.1.S.C.pcm |
| PWM | FOS.H12INVITRO.1.S.C.pwm |
| PFM | FOS.H12INVITRO.1.S.C.pfm |
| Alignment | FOS.H12INVITRO.1.S.C.words.tsv |
| Threshold to P-value map | FOS.H12INVITRO.1.S.C.thr |
| Motif in other formats | |
| JASPAR format | FOS.H12INVITRO.1.S.C_jaspar_format.txt |
| MEME format | FOS.H12INVITRO.1.S.C_meme_format.meme |
| Transfac format | FOS.H12INVITRO.1.S.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1684.25 | 2497.25 | 2307.25 | 2084.25 |
| 02 | 2895.25 | 1470.25 | 3002.25 | 1205.25 |
| 03 | 371.0 | 5350.0 | 611.0 | 2241.0 |
| 04 | 568.0 | 252.0 | 7719.0 | 34.0 |
| 05 | 0.0 | 1.0 | 0.0 | 8572.0 |
| 06 | 18.0 | 8555.0 | 0.0 | 0.0 |
| 07 | 8417.0 | 155.0 | 1.0 | 0.0 |
| 08 | 54.0 | 1490.0 | 57.0 | 6972.0 |
| 09 | 1175.75 | 4253.75 | 1450.75 | 1692.75 |
| 10 | 2802.5 | 2502.5 | 2122.5 | 1145.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.196 | 0.291 | 0.269 | 0.243 |
| 02 | 0.338 | 0.171 | 0.35 | 0.141 |
| 03 | 0.043 | 0.624 | 0.071 | 0.261 |
| 04 | 0.066 | 0.029 | 0.9 | 0.004 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 0.002 | 0.998 | 0.0 | 0.0 |
| 07 | 0.982 | 0.018 | 0.0 | 0.0 |
| 08 | 0.006 | 0.174 | 0.007 | 0.813 |
| 09 | 0.137 | 0.496 | 0.169 | 0.197 |
| 10 | 0.327 | 0.292 | 0.248 | 0.134 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.241 | 0.153 | 0.074 | -0.028 |
| 02 | 0.3 | -0.376 | 0.337 | -0.575 |
| 03 | -1.749 | 0.914 | -1.252 | 0.045 |
| 04 | -1.325 | -2.133 | 1.281 | -4.08 |
| 05 | -6.854 | -6.488 | -6.854 | 1.385 |
| 06 | -4.662 | 1.383 | -6.854 | -6.854 |
| 07 | 1.367 | -2.613 | -6.488 | -6.854 |
| 08 | -3.641 | -0.363 | -3.589 | 1.179 |
| 09 | -0.6 | 0.685 | -0.39 | -0.236 |
| 10 | 0.268 | 0.155 | -0.01 | -0.626 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.153315 |
| 0.0005 | 6.10106 |
| 0.0001 | 7.583535 |