FOS.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOS.H12INVITRO.0.P.B
Gene (human)	FOS (GeneCards)
Gene synonyms (human)	G0S7
Gene (mouse)	Fos
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	nTGMGTCAbnn
GC content	45.98%
Information content (bits; total / per base)	9.8 / 0.891
Data sources	ChIP-Seq
Aligned words	1009

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	25 (159)	0.871	0.991	0.838	0.974	0.874	0.991	3.654	5.479	258.301	611.292
Mouse	27 (180)	0.925	0.981	0.877	0.959	0.917	0.977	3.736	4.628	259.173	627.187

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.714	0.662	0.655	0.617	0.613	0.587
Non-Methyl HT-SELEX, 1 experiments	best	0.714	0.662	0.655	0.617	0.613	0.587

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.61	0.016	0.08	-0.049

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.1
HGNC	HGNC:3796
MGI	MGI:95574
EntrezGene (human)	GeneID:2353 (SSTAR profile)
EntrezGene (mouse)	GeneID:14281 (SSTAR profile)
UniProt ID (human)	FOS_HUMAN
UniProt ID (mouse)	FOS_MOUSE
UniProt AC (human)	P01100 (TFClass)
UniProt AC (mouse)	P01101 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	25 human, 27 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	FOS.H12INVITRO.0.P.B.pcm
PWM	FOS.H12INVITRO.0.P.B.pwm
PFM	FOS.H12INVITRO.0.P.B.pfm
Alignment	FOS.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	FOS.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	FOS.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	FOS.H12INVITRO.0.P.B_meme_format.meme
Transfac format	FOS.H12INVITRO.0.P.B_transfac_format.txt
Homer format	FOS.H12INVITRO.0.P.B_homer_format_0.001.txt FOS.H12INVITRO.0.P.B_homer_format_0.0005.txt FOS.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	271.0	242.0	280.0	216.0
02	25.0	7.0	20.0	957.0
03	9.0	35.0	858.0	107.0
04	767.0	121.0	12.0	109.0
05	164.0	0.0	843.0	2.0
06	43.0	62.0	31.0	873.0
07	71.0	892.0	33.0	13.0
08	993.0	6.0	2.0	8.0
09	64.0	359.0	259.0	327.0
10	246.0	387.0	159.0	217.0
11	281.0	242.0	253.0	233.0

PFM

	A	C	G	T
01	0.269	0.24	0.278	0.214
02	0.025	0.007	0.02	0.948
03	0.009	0.035	0.85	0.106
04	0.76	0.12	0.012	0.108
05	0.163	0.0	0.835	0.002
06	0.043	0.061	0.031	0.865
07	0.07	0.884	0.033	0.013
08	0.984	0.006	0.002	0.008
09	0.063	0.356	0.257	0.324
10	0.244	0.384	0.158	0.215
11	0.278	0.24	0.251	0.231

PWM

	A	C	G	T
01	0.071	-0.041	0.104	-0.154
02	-2.251	-3.371	-2.459	1.328
03	-3.164	-1.934	1.219	-0.848
04	1.107	-0.727	-2.918	-0.83
05	-0.427	-4.99	1.202	-4.221
06	-1.737	-1.383	-2.049	1.237
07	-1.251	1.258	-1.99	-2.847
08	1.365	-3.492	-4.221	-3.262
09	-1.352	0.351	0.026	0.258
10	-0.025	0.426	-0.458	-0.149
11	0.107	-0.041	0.003	-0.079

Standard thresholds

P-value	Threshold
0.001	4.78956
0.0005	5.623085
0.0001	7.28209