MotifFOS.H12CORE.0.P.B
Gene (human)FOS
(GeneCards)
Gene synonyms (human)G0S7
Gene (mouse)Fos
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnTGMGTCAbnn
GC content45.98%
Information content (bits; total / per base)9.8 / 0.891
Data sourcesChIP-Seq
Aligned words1009

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 25 (159) 0.871 0.991 0.838 0.974 0.874 0.991 3.654 5.479 258.301 611.292
Mouse 27 (180) 0.925 0.981 0.877 0.959 0.917 0.977 3.736 4.628 259.173 627.187

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 1 experiments median 0.714 0.662 0.655 0.617 0.613 0.587
best 0.714 0.662 0.655 0.617 0.613 0.587

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.61 0.016 0.08 -0.049
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyFos-related {1.1.2} (TFClass)
TF subfamilyFos {1.1.2.1} (TFClass)
TFClass IDTFClass: 1.1.2.1.1
HGNCHGNC:3796
MGIMGI:95574
EntrezGene (human)GeneID:2353
(SSTAR profile)
EntrezGene (mouse)GeneID:14281
(SSTAR profile)
UniProt ID (human)FOS_HUMAN
UniProt ID (mouse)FOS_MOUSE
UniProt AC (human)P01100
(TFClass)
UniProt AC (mouse)P01101
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 25 human, 27 mouse
HT-SELEX 1
Methyl-HT-SELEX 0
PCM
ACGT
01271.0242.0280.0216.0
0225.07.020.0957.0
039.035.0858.0107.0
04767.0121.012.0109.0
05164.00.0843.02.0
0643.062.031.0873.0
0771.0892.033.013.0
08993.06.02.08.0
0964.0359.0259.0327.0
10246.0387.0159.0217.0
11281.0242.0253.0233.0
PFM
ACGT
010.2690.240.2780.214
020.0250.0070.020.948
030.0090.0350.850.106
040.760.120.0120.108
050.1630.00.8350.002
060.0430.0610.0310.865
070.070.8840.0330.013
080.9840.0060.0020.008
090.0630.3560.2570.324
100.2440.3840.1580.215
110.2780.240.2510.231
PWM
ACGT
010.071-0.0410.104-0.154
02-2.251-3.371-2.4591.328
03-3.164-1.9341.219-0.848
041.107-0.727-2.918-0.83
05-0.427-4.991.202-4.221
06-1.737-1.383-2.0491.237
07-1.2511.258-1.99-2.847
081.365-3.492-4.221-3.262
09-1.3520.3510.0260.258
10-0.0250.426-0.458-0.149
110.107-0.0410.003-0.079
Standard thresholds
P-value Threshold
0.001 4.78956
0.0005 5.623085
0.0001 7.28209