MotifFLI1.H12INVITRO.1.P.B
Gene (human)FLI1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Fli1
Gene synonyms (mouse)Fli-1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length18
ConsensusvRRMMGGAARnRvvdvvv
GC content56.25%
Information content (bits; total / per base)12.985 / 0.721
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 35 (207) 0.822 0.985 0.668 0.972 0.864 0.991 3.204 7.099 95.585 292.42
Mouse 25 (133) 0.802 0.89 0.622 0.777 0.836 0.9 2.791 3.488 69.886 200.201

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 9 experiments median 0.835 0.774 0.733 0.695 0.628 0.625
best 0.968 0.943 0.948 0.92 0.864 0.844
Methyl HT-SELEX, 2 experiments median 0.626 0.593 0.569 0.557 0.535 0.535
best 0.632 0.594 0.579 0.56 0.542 0.538
Non-Methyl HT-SELEX, 7 experiments median 0.909 0.86 0.823 0.784 0.702 0.694
best 0.968 0.943 0.948 0.92 0.864 0.844

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.913 9.627 0.224 0.146

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.732 0.332 0.696 0.484
batch 2 0.651 0.484 0.601 0.362
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyETS-like {3.5.2.1} (TFClass)
TFClass IDTFClass: 3.5.2.1.6
HGNCHGNC:3749
MGIMGI:95554
EntrezGene (human)GeneID:2313
(SSTAR profile)
EntrezGene (mouse)GeneID:14247
(SSTAR profile)
UniProt ID (human)FLI1_HUMAN
UniProt ID (mouse)FLI1_MOUSE
UniProt AC (human)Q01543
(TFClass)
UniProt AC (mouse)P26323
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 35 human, 25 mouse
HT-SELEX 7
Methyl-HT-SELEX 2
PCM
ACGT
01312.0202.0382.0104.0
02264.065.0615.056.0
03427.044.0507.022.0
04295.0463.0236.06.0
05751.0190.07.052.0
061.01.0989.09.0
074.02.0993.01.0
08984.03.011.02.0
09979.03.04.014.0
10289.06.0648.057.0
11138.0229.0311.0322.0
12290.080.0559.071.0
13377.0109.0468.046.0
14379.0166.0400.055.0
15221.0134.0391.0254.0
16246.0156.0521.077.0
17219.0197.0450.0134.0
18282.0166.0417.0135.0
PFM
ACGT
010.3120.2020.3820.104
020.2640.0650.6150.056
030.4270.0440.5070.022
040.2950.4630.2360.006
050.7510.190.0070.052
060.0010.0010.9890.009
070.0040.0020.9930.001
080.9840.0030.0110.002
090.9790.0030.0040.014
100.2890.0060.6480.057
110.1380.2290.3110.322
120.290.080.5590.071
130.3770.1090.4680.046
140.3790.1660.40.055
150.2210.1340.3910.254
160.2460.1560.5210.077
170.2190.1970.450.134
180.2820.1660.4170.135
PWM
ACGT
010.22-0.2120.422-0.867
020.054-1.3280.896-1.473
030.532-1.7060.704-2.362
040.1640.613-0.057-3.484
051.095-0.272-3.362-1.544
06-4.525-4.5251.37-3.156
07-3.783-4.2131.374-4.525
081.365-3.975-2.985-4.213
091.36-3.975-3.783-2.773
100.144-3.4840.948-1.455
11-0.589-0.0870.2170.252
120.147-1.1250.801-1.242
130.408-0.8210.624-1.663
140.414-0.4060.467-1.49
15-0.122-0.6180.4450.016
16-0.016-0.4670.731-1.162
17-0.131-0.2360.585-0.618
180.12-0.4060.509-0.61
Standard thresholds
P-value Threshold
0.001 3.63411
0.0005 4.79201
0.0001 7.16366