FIGLA.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FIGLA.H12INVITRO.0.SM.B
Gene (human)	FIGLA (GeneCards)
Gene synonyms (human)	BHLHC8
Gene (mouse)	Figla
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	nhvCACCTGKd
GC content	55.01%
Information content (bits; total / per base)	13.079 / 1.189
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9802

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.995	0.991	0.993	0.988	0.991	0.985
Overall, 3 experiments	best	0.996	0.993	0.995	0.992	0.994	0.989
Methyl HT-SELEX, 1 experiments	median	0.996	0.993	0.995	0.992	0.994	0.989
Methyl HT-SELEX, 1 experiments	best	0.996	0.993	0.995	0.992	0.994	0.989
Non-Methyl HT-SELEX, 2 experiments	median	0.846	0.84	0.79	0.794	0.765	0.77
Non-Methyl HT-SELEX, 2 experiments	best	0.995	0.991	0.993	0.988	0.991	0.985

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.978	0.855	0.959	0.547
batch 2	0.963	0.775	0.951	0.561

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TWIST {1.2.3.2} (TFClass)
TFClass ID	TFClass: 1.2.3.2.8
HGNC	HGNC:24669
MGI	MGI:1349421
EntrezGene (human)	GeneID:344018 (SSTAR profile)
EntrezGene (mouse)	GeneID:26910 (SSTAR profile)
UniProt ID (human)	FIGLA_HUMAN
UniProt ID (mouse)	FIGLA_MOUSE
UniProt AC (human)	Q6QHK4 (TFClass)
UniProt AC (mouse)	O55208 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	1

PCM	FIGLA.H12INVITRO.0.SM.B.pcm
PWM	FIGLA.H12INVITRO.0.SM.B.pwm
PFM	FIGLA.H12INVITRO.0.SM.B.pfm
Alignment	FIGLA.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	FIGLA.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	FIGLA.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	FIGLA.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	FIGLA.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	FIGLA.H12INVITRO.0.SM.B_homer_format_0.001.txt FIGLA.H12INVITRO.0.SM.B_homer_format_0.0005.txt FIGLA.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2175.5	2676.5	1693.5	3256.5
02	4551.0	1521.0	877.0	2853.0
03	3337.0	4128.0	1195.0	1142.0
04	3.0	9797.0	0.0	2.0
05	9802.0	0.0	0.0	0.0
06	0.0	9802.0	0.0	0.0
07	0.0	9802.0	0.0	0.0
08	0.0	0.0	0.0	9802.0
09	0.0	0.0	9801.0	1.0
10	500.0	613.0	4185.0	4504.0
11	2698.0	1521.0	1704.0	3879.0

PFM

	A	C	G	T
01	0.222	0.273	0.173	0.332
02	0.464	0.155	0.089	0.291
03	0.34	0.421	0.122	0.117
04	0.0	0.999	0.0	0.0
05	1.0	0.0	0.0	0.0
06	0.0	1.0	0.0	0.0
07	0.0	1.0	0.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.0	1.0	0.0
10	0.051	0.063	0.427	0.459
11	0.275	0.155	0.174	0.396

PWM

	A	C	G	T
01	-0.119	0.088	-0.369	0.284
02	0.619	-0.476	-1.026	0.152
03	0.309	0.521	-0.717	-0.762
04	-6.138	1.385	-6.973	-6.347
05	1.386	-6.973	-6.973	-6.973
06	-6.973	1.386	-6.973	-6.973
07	-6.973	1.386	-6.973	-6.973
08	-6.973	-6.973	-6.973	1.386
09	-6.973	-6.973	1.385	-6.612
10	-1.586	-1.383	0.535	0.608
11	0.096	-0.476	-0.363	0.459

Standard thresholds

P-value	Threshold
0.001	0.627335
0.0005	1.40741
0.0001	7.7951