EVX2.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	EVX2.H12INVITRO.1.S.B
Gene (human)	EVX2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Evx2
Gene synonyms (mouse)	Evx-2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	19
Consensus	nbvSTAATTASYnhhhWdh
GC content	33.08%
Information content (bits; total / per base)	16.654 / 0.877
Data sources	HT-SELEX
Aligned words	661

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.989	0.982	0.979	0.968	0.946	0.93
Overall, 4 experiments	best	0.991	0.986	0.982	0.972	0.959	0.944
Methyl HT-SELEX, 1 experiments	median	0.991	0.986	0.982	0.972	0.959	0.944
Methyl HT-SELEX, 1 experiments	best	0.991	0.986	0.982	0.972	0.959	0.944
Non-Methyl HT-SELEX, 3 experiments	median	0.989	0.981	0.979	0.968	0.937	0.923
Non-Methyl HT-SELEX, 3 experiments	best	0.99	0.984	0.979	0.968	0.954	0.937

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.633	0.317	0.596	0.408

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HOX-related {3.1.1} (TFClass)
TF subfamily	EVX {3.1.1.10} (TFClass)
TFClass ID	TFClass: 3.1.1.10.2
HGNC	HGNC:3507
MGI	MGI:95462
EntrezGene (human)	GeneID:344191 (SSTAR profile)
EntrezGene (mouse)	GeneID:14029 (SSTAR profile)
UniProt ID (human)	EVX2_HUMAN
UniProt ID (mouse)	EVX2_MOUSE
UniProt AC (human)	Q03828 (TFClass)
UniProt AC (mouse)	P49749 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	EVX2.H12INVITRO.1.S.B.pcm
PWM	EVX2.H12INVITRO.1.S.B.pwm
PFM	EVX2.H12INVITRO.1.S.B.pfm
Alignment	EVX2.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	EVX2.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	EVX2.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	EVX2.H12INVITRO.1.S.B_meme_format.meme
Transfac format	EVX2.H12INVITRO.1.S.B_transfac_format.txt
Homer format	EVX2.H12INVITRO.1.S.B_homer_format_0.001.txt EVX2.H12INVITRO.1.S.B_homer_format_0.0005.txt EVX2.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	110.5	222.5	209.5	118.5
02	72.0	315.0	194.0	80.0
03	227.0	173.0	240.0	21.0
04	5.0	493.0	102.0	61.0
05	0.0	1.0	0.0	660.0
06	643.0	13.0	5.0	0.0
07	661.0	0.0	0.0	0.0
08	0.0	0.0	0.0	661.0
09	0.0	27.0	9.0	625.0
10	661.0	0.0	0.0	0.0
11	57.0	150.0	451.0	3.0
12	13.0	211.0	96.0	341.0
13	148.0	150.0	249.0	114.0
14	282.0	203.0	68.0	108.0
15	164.0	102.0	37.0	358.0
16	240.0	77.0	29.0	315.0
17	434.0	11.0	10.0	206.0
18	270.25	39.25	56.25	295.25
19	157.25	108.25	103.25	292.25

PFM

	A	C	G	T
01	0.167	0.337	0.317	0.179
02	0.109	0.477	0.293	0.121
03	0.343	0.262	0.363	0.032
04	0.008	0.746	0.154	0.092
05	0.0	0.002	0.0	0.998
06	0.973	0.02	0.008	0.0
07	1.0	0.0	0.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.041	0.014	0.946
10	1.0	0.0	0.0	0.0
11	0.086	0.227	0.682	0.005
12	0.02	0.319	0.145	0.516
13	0.224	0.227	0.377	0.172
14	0.427	0.307	0.103	0.163
15	0.248	0.154	0.056	0.542
16	0.363	0.116	0.044	0.477
17	0.657	0.017	0.015	0.312
18	0.409	0.059	0.085	0.447
19	0.238	0.164	0.156	0.442

PWM

	A	C	G	T
01	-0.398	0.295	0.235	-0.329
02	-0.818	0.64	0.159	-0.715
03	0.315	0.045	0.37	-1.998
04	-3.227	1.087	-0.476	-0.98
05	-4.633	-4.153	-4.633	1.377
06	1.351	-2.435	-3.227	-4.633
07	1.379	-4.633	-4.633	-4.633
08	-4.633	-4.633	-4.633	1.379
09	-4.633	-1.763	-2.754	1.323
10	1.379	-4.633	-4.633	-4.633
11	-1.046	-0.096	0.998	-3.586
12	-2.435	0.242	-0.536	0.719
13	-0.109	-0.096	0.407	-0.367
14	0.53	0.204	-0.874	-0.42
15	-0.008	-0.476	-1.463	0.768
16	0.37	-0.753	-1.695	0.64
17	0.96	-2.582	-2.664	0.218
18	0.488	-1.407	-1.059	0.576
19	-0.049	-0.418	-0.464	0.566

Standard thresholds

P-value	Threshold
0.001	1.46736
0.0005	2.91591
0.0001	5.90286