Motif | EVX2.H12CORE.1.S.B |
Gene (human) | EVX2 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Evx2 |
Gene synonyms (mouse) | Evx-2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | EVX2.H12CORE.1.S.B |
Gene (human) | EVX2 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Evx2 |
Gene synonyms (mouse) | Evx-2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 17 |
Consensus | hWdWdnRYTAATTASbv |
GC content | 30.42% |
Information content (bits; total / per base) | 15.696 / 0.923 |
Data sources | HT-SELEX |
Aligned words | 355 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.987 | 0.979 | 0.977 | 0.965 | 0.95 | 0.933 |
best | 0.989 | 0.983 | 0.98 | 0.969 | 0.96 | 0.944 | |
Methyl HT-SELEX, 1 experiments | median | 0.989 | 0.983 | 0.98 | 0.969 | 0.96 | 0.944 |
best | 0.989 | 0.983 | 0.98 | 0.969 | 0.96 | 0.944 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.987 | 0.977 | 0.977 | 0.965 | 0.942 | 0.926 |
best | 0.988 | 0.98 | 0.978 | 0.965 | 0.958 | 0.94 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 2 | 0.656 | 0.334 | 0.652 | 0.443 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HOX-related {3.1.1} (TFClass) |
TF subfamily | EVX {3.1.1.10} (TFClass) |
TFClass ID | TFClass: 3.1.1.10.2 |
HGNC | HGNC:3507 |
MGI | MGI:95462 |
EntrezGene (human) | GeneID:344191 (SSTAR profile) |
EntrezGene (mouse) | GeneID:14029 (SSTAR profile) |
UniProt ID (human) | EVX2_HUMAN |
UniProt ID (mouse) | EVX2_MOUSE |
UniProt AC (human) | Q03828 (TFClass) |
UniProt AC (mouse) | P49749 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | EVX2.H12CORE.1.S.B.pcm |
PWM | EVX2.H12CORE.1.S.B.pwm |
PFM | EVX2.H12CORE.1.S.B.pfm |
Alignment | EVX2.H12CORE.1.S.B.words.tsv |
Threshold to P-value map | EVX2.H12CORE.1.S.B.thr |
Motif in other formats | |
JASPAR format | EVX2.H12CORE.1.S.B_jaspar_format.txt |
MEME format | EVX2.H12CORE.1.S.B_meme_format.meme |
Transfac format | EVX2.H12CORE.1.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 138.0 | 50.0 | 38.0 | 129.0 |
02 | 103.25 | 13.25 | 11.25 | 227.25 |
03 | 191.0 | 18.0 | 48.0 | 98.0 |
04 | 208.0 | 10.0 | 39.0 | 98.0 |
05 | 45.0 | 35.0 | 91.0 | 184.0 |
06 | 68.0 | 132.0 | 81.0 | 74.0 |
07 | 196.0 | 51.0 | 104.0 | 4.0 |
08 | 4.0 | 255.0 | 47.0 | 49.0 |
09 | 0.0 | 0.0 | 0.0 | 355.0 |
10 | 341.0 | 7.0 | 7.0 | 0.0 |
11 | 355.0 | 0.0 | 0.0 | 0.0 |
12 | 0.0 | 0.0 | 0.0 | 355.0 |
13 | 0.0 | 10.0 | 17.0 | 328.0 |
14 | 353.0 | 0.0 | 2.0 | 0.0 |
15 | 39.0 | 66.0 | 231.0 | 19.0 |
16 | 12.75 | 125.75 | 110.75 | 105.75 |
17 | 63.0 | 91.0 | 145.0 | 56.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.389 | 0.141 | 0.107 | 0.363 |
02 | 0.291 | 0.037 | 0.032 | 0.64 |
03 | 0.538 | 0.051 | 0.135 | 0.276 |
04 | 0.586 | 0.028 | 0.11 | 0.276 |
05 | 0.127 | 0.099 | 0.256 | 0.518 |
06 | 0.192 | 0.372 | 0.228 | 0.208 |
07 | 0.552 | 0.144 | 0.293 | 0.011 |
08 | 0.011 | 0.718 | 0.132 | 0.138 |
09 | 0.0 | 0.0 | 0.0 | 1.0 |
10 | 0.961 | 0.02 | 0.02 | 0.0 |
11 | 1.0 | 0.0 | 0.0 | 0.0 |
12 | 0.0 | 0.0 | 0.0 | 1.0 |
13 | 0.0 | 0.028 | 0.048 | 0.924 |
14 | 0.994 | 0.0 | 0.006 | 0.0 |
15 | 0.11 | 0.186 | 0.651 | 0.054 |
16 | 0.036 | 0.354 | 0.312 | 0.298 |
17 | 0.177 | 0.256 | 0.408 | 0.158 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.436 | -0.561 | -0.827 | 0.369 |
02 | 0.149 | -1.813 | -1.959 | 0.93 |
03 | 0.758 | -1.533 | -0.601 | 0.098 |
04 | 0.842 | -2.063 | -0.802 | 0.098 |
05 | -0.663 | -0.906 | 0.025 | 0.721 |
06 | -0.261 | 0.392 | -0.09 | -0.179 |
07 | 0.783 | -0.542 | 0.156 | -2.803 |
08 | -2.803 | 1.045 | -0.621 | -0.581 |
09 | -4.118 | -4.118 | -4.118 | 1.374 |
10 | 1.334 | -2.366 | -2.366 | -4.118 |
11 | 1.374 | -4.118 | -4.118 | -4.118 |
12 | -4.118 | -4.118 | -4.118 | 1.374 |
13 | -4.118 | -2.063 | -1.586 | 1.295 |
14 | 1.368 | -4.118 | -3.259 | -4.118 |
15 | -0.802 | -0.291 | 0.947 | -1.483 |
16 | -1.848 | 0.344 | 0.218 | 0.173 |
17 | -0.336 | 0.025 | 0.485 | -0.451 |
P-value | Threshold |
---|---|
0.001 | 2.51751 |
0.0005 | 3.80321 |
0.0001 | 6.46786 |