MotifEVX1.H12INVIVO.0.SM.D
Gene (human)EVX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Evx1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length12
ConsensusnhvhTAATYAbn
GC content34.11%
Information content (bits; total / per base)10.609 / 0.884
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words6355

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.971 0.954 0.942 0.918 0.868 0.85
best 0.977 0.963 0.96 0.938 0.931 0.904
Methyl HT-SELEX, 1 experiments median 0.975 0.96 0.96 0.938 0.931 0.904
best 0.975 0.96 0.96 0.938 0.931 0.904
Non-Methyl HT-SELEX, 3 experiments median 0.966 0.948 0.926 0.9 0.809 0.8
best 0.977 0.963 0.958 0.937 0.927 0.899

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.752 0.565 0.749 0.553
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyEVX {3.1.1.10} (TFClass)
TFClass IDTFClass: 3.1.1.10.1
HGNCHGNC:3506
MGIMGI:95461
EntrezGene (human)GeneID:2128
(SSTAR profile)
EntrezGene (mouse)GeneID:14028
(SSTAR profile)
UniProt ID (human)EVX1_HUMAN
UniProt ID (mouse)EVX1_MOUSE
UniProt AC (human)P49640
(TFClass)
UniProt AC (mouse)P23683
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011525.751781.751577.751469.75
021050.52532.5787.51984.5
032258.01470.02385.0242.0
041737.03364.0468.0786.0
050.00.00.06355.0
066355.00.00.00.0
076355.00.00.00.0
080.00.00.06355.0
097.02296.01284.02768.0
105380.055.0808.0112.0
11958.52636.51379.51380.5
121507.751785.751401.751659.75
PFM
ACGT
010.240.280.2480.231
020.1650.3990.1240.312
030.3550.2310.3750.038
040.2730.5290.0740.124
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.0010.3610.2020.436
100.8470.0090.1270.018
110.1510.4150.2170.217
120.2370.2810.2210.261
PWM
ACGT
01-0.040.114-0.007-0.078
02-0.4130.466-0.70.222
030.351-0.0780.406-1.874
040.0890.749-1.219-0.702
05-6.589-6.589-6.5891.385
061.385-6.589-6.589-6.589
071.385-6.589-6.589-6.589
08-6.589-6.589-6.5891.385
09-5.1540.368-0.2130.555
101.219-3.326-0.675-2.634
11-0.5040.506-0.141-0.14
12-0.0520.117-0.1250.044
Standard thresholds
P-value Threshold
0.001 4.62424
0.0005 6.050515
0.0001 7.774845