ETV7.H12RSNP.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV7.H12RSNP.1.P.C
Gene (human)	ETV7 (GeneCards)
Gene synonyms (human)	TEL2, TELB, TREF
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	7
Consensus	vRGGAAR
GC content	50.36%
Information content (bits; total / per base)	8.712 / 1.245
Data sources	ChIP-Seq
Aligned words	1082

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.594	0.61	0.4	0.427	0.627	0.634	1.304	1.313	1.046	1.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.898	0.875	0.844	0.81	0.78	0.763
Overall, 2 experiments	best	0.945	0.925	0.925	0.886	0.927	0.881
Methyl HT-SELEX, 1 experiments	median	0.851	0.825	0.763	0.734	0.633	0.645
Methyl HT-SELEX, 1 experiments	best	0.851	0.825	0.763	0.734	0.633	0.645
Non-Methyl HT-SELEX, 1 experiments	median	0.945	0.925	0.925	0.886	0.927	0.881
Non-Methyl HT-SELEX, 1 experiments	best	0.945	0.925	0.925	0.886	0.927	0.881

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.811	0.174	0.645	0.404

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETV6-like {3.5.2.6} (TFClass)
TFClass ID	TFClass: 3.5.2.6.2
HGNC	HGNC:18160
MGI
EntrezGene (human)	GeneID:51513 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ETV7_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9Y603 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ETV7.H12RSNP.1.P.C.pcm
PWM	ETV7.H12RSNP.1.P.C.pwm
PFM	ETV7.H12RSNP.1.P.C.pfm
Alignment	ETV7.H12RSNP.1.P.C.words.tsv
Threshold to P-value map	ETV7.H12RSNP.1.P.C.thr
Motif in other formats
JASPAR format	ETV7.H12RSNP.1.P.C_jaspar_format.txt
MEME format	ETV7.H12RSNP.1.P.C_meme_format.meme
Transfac format	ETV7.H12RSNP.1.P.C_transfac_format.txt
Homer format	ETV7.H12RSNP.1.P.C_homer_format_0.001.txt ETV7.H12RSNP.1.P.C_homer_format_0.0005.txt ETV7.H12RSNP.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	237.0	472.0	304.0	69.0
02	740.0	92.0	171.0	79.0
03	5.0	1.0	1070.0	6.0
04	10.0	16.0	1050.0	6.0
05	1060.0	6.0	11.0	5.0
06	1028.0	2.0	46.0	6.0
07	470.0	23.0	550.0	39.0

PFM

	A	C	G	T
01	0.219	0.436	0.281	0.064
02	0.684	0.085	0.158	0.073
03	0.005	0.001	0.989	0.006
04	0.009	0.015	0.97	0.006
05	0.98	0.006	0.01	0.005
06	0.95	0.002	0.043	0.006
07	0.434	0.021	0.508	0.036

PWM

	A	C	G	T
01	-0.131	0.554	0.116	-1.348
02	1.002	-1.066	-0.455	-1.215
03	-3.698	-4.596	1.37	-3.559
04	-3.143	-2.731	1.351	-3.559
05	1.361	-3.559	-3.061	-3.698
06	1.33	-4.286	-1.741	-3.559
07	0.55	-2.398	0.706	-1.899

Standard thresholds

P-value	Threshold
0.001	5.34686
0.0005	5.792095
0.0001	7.400645