ETV7.H12INVIVO.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV7.H12INVIVO.1.P.C
Gene (human)	ETV7 (GeneCards)
Gene synonyms (human)	TEL2, TELB, TREF
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	7
Consensus	vAGGAAR
GC content	49.01%
Information content (bits; total / per base)	10.199 / 1.457
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.598	0.61	0.408	0.427	0.629	0.641	1.31	1.327	3.0	4.658

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.889	0.862	0.83	0.796	0.768	0.749
Overall, 2 experiments	best	0.937	0.914	0.915	0.873	0.913	0.864
Methyl HT-SELEX, 1 experiments	median	0.84	0.81	0.744	0.718	0.623	0.634
Methyl HT-SELEX, 1 experiments	best	0.84	0.81	0.744	0.718	0.623	0.634
Non-Methyl HT-SELEX, 1 experiments	median	0.937	0.914	0.915	0.873	0.913	0.864
Non-Methyl HT-SELEX, 1 experiments	best	0.937	0.914	0.915	0.873	0.913	0.864

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.774	0.157	0.603	0.358

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETV6-like {3.5.2.6} (TFClass)
TFClass ID	TFClass: 3.5.2.6.2
HGNC	HGNC:18160
MGI
EntrezGene (human)	GeneID:51513 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ETV7_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9Y603 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ETV7.H12INVIVO.1.P.C.pcm
PWM	ETV7.H12INVIVO.1.P.C.pwm
PFM	ETV7.H12INVIVO.1.P.C.pfm
Alignment	ETV7.H12INVIVO.1.P.C.words.tsv
Threshold to P-value map	ETV7.H12INVIVO.1.P.C.thr
Motif in other formats
JASPAR format	ETV7.H12INVIVO.1.P.C_jaspar_format.txt
MEME format	ETV7.H12INVIVO.1.P.C_meme_format.meme
Transfac format	ETV7.H12INVIVO.1.P.C_transfac_format.txt
Homer format	ETV7.H12INVIVO.1.P.C_homer_format_0.001.txt ETV7.H12INVIVO.1.P.C_homer_format_0.0005.txt ETV7.H12INVIVO.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	253.0	488.0	238.0	21.0
02	944.0	50.0	4.0	2.0
03	2.0	2.0	995.0	1.0
04	10.0	16.0	970.0	4.0
05	995.0	1.0	4.0	0.0
06	975.0	2.0	16.0	7.0
07	324.0	39.0	606.0	31.0

PFM

	A	C	G	T
01	0.253	0.488	0.238	0.021
02	0.944	0.05	0.004	0.002
03	0.002	0.002	0.995	0.001
04	0.01	0.016	0.97	0.004
05	0.995	0.001	0.004	0.0
06	0.975	0.002	0.016	0.007
07	0.324	0.039	0.606	0.031

PWM

	A	C	G	T
01	0.012	0.666	-0.049	-2.405
02	1.324	-1.582	-3.783	-4.213
03	-4.213	-4.213	1.376	-4.525
04	-3.066	-2.653	1.351	-3.783
05	1.376	-4.525	-3.783	-4.982
06	1.356	-4.213	-2.653	-3.362
07	0.258	-1.821	0.881	-2.04

Standard thresholds

P-value	Threshold
0.001	4.668575
0.0005	5.342115
0.0001	7.723835